Silvia Corvera
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Explore the profile of Silvia Corvera including associated specialties, affiliations and a list of published articles.
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63
Citations
3252
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Recent Articles
1.
Desai A, Loureiro Z, DeSouza T, Yang Q, Solivan-Rivera J, Corvera S
Mol Metab
. 2024 Oct;
90:102051.
PMID: 39454826
Objective: The uncoupling protein 1 (UCP1) is induced in brown or "beige" adipocytes through catecholamine-induced cAMP signaling, which activates diverse transcription factors. UCP1 expression can also be enhanced by PPARγ...
2.
Desai A, Loureiro Z, DeSouza T, Yang Q, Solivan-Rivera J, Corvera S
bioRxiv
. 2024 Aug;
PMID: 39211160
Objective: The uncoupling protein 1 (UCP1) is induced in brown or "beige" adipocytes through catecholamine-induced cAMP signaling, which activates diverse transcription factors. UCP1 expression can also be enhanced by PPARγ...
3.
Nguyen T, Corvera S
Nat Metab
. 2024 May;
6(5):793-807.
PMID: 38783156
Ageing is a conserved biological process, modulated by intrinsic and extrinsic factors, that leads to changes in life expectancy. In humans, ageing is characterized by greatly increased prevalence of cardiometabolic...
4.
OReilly M, Ho S, Coronel J, Zhu L, Liu W, Xue C, et al.
Cell Rep
. 2024 May;
43(5):114240.
PMID: 38753486
Adipose tissue remodeling and dysfunction, characterized by elevated inflammation and insulin resistance, play a central role in obesity-related development of type 2 diabetes (T2D) and cardiovascular diseases. Long intergenic non-coding...
5.
Yang Q, Loureiro Z, Desai A, DeSouza T, Li K, Wang H, et al.
PNAS Nexus
. 2023 Dec;
2(12):pgad420.
PMID: 38130664
Adipocyte lipid droplets (LDs) play a crucial role in systemic lipid metabolism by storing and releasing lipids to meet the organism's energy needs. Hormonal signals such as catecholamines and insulin...
6.
Nguyen T, Loureiro Z, Desai A, DeSouza T, Joyce S, Khair L, et al.
bioRxiv
. 2023 Sep;
PMID: 37693594
Aging and metabolic diseases are accompanied by systemic inflammation, but the mechanisms that induce this state are not known. We developed a human bone-marrow organoid system to explore mechanisms underlying...
7.
Loureiro Z, Joyce S, DeSouza T, Solivan-Rivera J, Desai A, Skritakis P, et al.
Nat Metab
. 2023 Jun;
5(6):1014-1028.
PMID: 37337125
Mesenchymal stem/progenitor cells are essential for tissue development and repair throughout life, but how they are maintained under chronic differentiation pressure is not known. Using single-cell transcriptomics of human progenitor...
8.
Solivan-Rivera J, Loureiro Z, DeSouza T, Desai A, Pallat S, Yang Q, et al.
Elife
. 2022 Sep;
11.
PMID: 36107478
Mechanisms that control 'beige/brite' thermogenic adipose tissue development may be harnessed to improve human metabolic health. To define these mechanisms, we developed a species-hybrid model in which human mesenchymal progenitor...
9.
10.
Corvera S, Solivan-Rivera J, Loureiro Z
Angiogenesis
. 2022 Jul;
25(4):439-453.
PMID: 35857195
While most tissues exhibit their greatest growth during development, adipose tissue is capable of additional massive expansion in adults. Adipose tissue expandability is advantageous when temporarily storing fuel for use...