Siji Li
Overview
Explore the profile of Siji Li including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
147
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0
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Recent Articles
1.
Li T, Li S
Int Immunopharmacol
. 2024 Mar;
131:111819.
PMID: 38460305
Mitochondria serve as a platform for innate immune signaling transduction, and mitochondrial antiviral signaling protein (MAVS) is essential for interferon-β (IFN-β) production and innate antiviral immunity against RNA viruses. Here,...
2.
Kuang M, Zhao Y, Yu H, Li S, Liu T, Chen L, et al.
Sci Adv
. 2023 Aug;
9(33):eadg5211.
PMID: 37595039
A rapid induction of antiviral genes is critical for eliminating viruses, which requires activated transcription factors and opened chromatins to initiate transcription. However, it remains elusive how the accessibility of...
3.
Ye Q, Xu G, Huang H, Pang S, Xie B, Feng B, et al.
Int J Gen Med
. 2023 Aug;
16:3331-3344.
PMID: 37576910
Purpose: Chronic kidney disease (CKD) progression is complex. There are not standardized methods for predicting the prognosis of CKD. Nicotinamide N-methyltransferase (NNMT) has been shown to be associated with renal...
4.
Cao L, Luo Y, Guo X, Liu S, Li S, Li J, et al.
PLoS Pathog
. 2022 Jun;
18(6):e1010599.
PMID: 35658050
Regulation of chromatin structure and accessibility determines the transcription activities of genes, which endows the host with function-specific patterns of gene expression. Upon viral infection, the innate immune responses provide...
5.
Li S, Cao L, Zhang Z, Kuang M, Chen L, Zhao Y, et al.
Mol Biomed
. 2022 Jan;
2(1):30.
PMID: 35006471
The innate immune system is the first line of host defense, which responds rapidly to viral infection. Innate recognition of viruses is mediated by a set of pattern recognition receptors...
6.
Du H, Xia H, Liu T, Li Y, Liu J, Xie B, et al.
iScience
. 2021 Mar;
24(3):102169.
PMID: 33665583
Ulcerative colitis (UC) is a chronic inflammatory bowel disease, characterized by relapsing and remitting colon mucosal inflammation. For patients suffering from UC, a higher risk of colon cancer has been...
7.
Li Y, Liu S, Cao L, Luo Y, Du H, Li S, et al.
RNA Biol
. 2021 Feb;
18(11):1608-1621.
PMID: 33596778
RNA and protein are interconnected biomolecules that can influence each other's life cycles and functions through physical interactions. Abnormal RNA-protein interactions lead to cell dysfunctions and human diseases. Therefore, mapping...
8.
Li S, Kuang M, Chen L, Li Y, Liu S, Du H, et al.
Cell Rep
. 2021 Jan;
34(3):108631.
PMID: 33472079
Mitochondria not only serve as a platform for innate immune signaling transduction but also enhance immune responses by releasing mitochondrial DNA and RNA into the cytoplasm. However, whether mitochondrial matrix...
9.
Cao L, Liu S, Li Y, Yang G, Luo Y, Li S, et al.
Cell Host Microbe
. 2019 Sep;
26(3):369-384.e8.
PMID: 31513772
Pathogen pattern recognition receptors (PRRs) trigger innate immune responses to invading pathogens. All known PRRs for viral RNA have extranuclear localization. However, for many viruses, replication generates dsRNA in the...
10.
The GRA15 protein from enhances host defense responses by activating the interferon stimulator STING
Wang P, Li S, Zhao Y, Zhang B, Li Y, Liu S, et al.
J Biol Chem
. 2019 Aug;
294(45):16494-16508.
PMID: 31416833
is an important neurotropic pathogen that establishes latent infections in humans that can cause toxoplasmosis in immunocompromised individuals. It replicates inside host cells and has developed several strategies to manipulate...