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Sigurd Braun

Explore the profile of Sigurd Braun including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 1119
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Recent Articles
1.
Skribbe M, Soneson C, Stadler M, Schwaiger M, Suma Sreechakram V, Iesmantavicius V, et al.
Mol Cell . 2025 Feb; PMID: 40015273
Transcription factors (TFs) are key regulators of gene expression, yet many of their targets and modes of action remain unknown. In Schizosaccharomyces pombe, one-third of TFs are solely homology predicted,...
2.
Jimenez-Martin A, Pineda-Santaella A, Martin-Garcia R, Esteban-Villafane R, Matarrese A, Pinto-Cruz J, et al.
Nat Commun . 2025 Jan; 16(1):837. PMID: 39833200
Accurate gametogenesis requires the establishment of the telomere bouquet, an evolutionarily conserved, 3D chromosomal arrangement. In this spatial configuration, telomeres temporarily aggregate at the nuclear envelope during meiotic prophase, which...
3.
Kanno H, Hiramatsu K, Mikami H, Nakayashiki A, Yamashita S, Nagai A, et al.
Nat Commun . 2025 Jan; 16(1):582. PMID: 39794325
No abstract available.
4.
Muhammad A, Sarkadi Z, Mazumder A, Ait Saada A, van Emden T, Capella M, et al.
Nucleic Acids Res . 2024 Nov; 52(22):13665-13689. PMID: 39565189
Heterochromatin plays a critical role in regulating gene expression and maintaining genome integrity. While structural and enzymatic components have been linked to heterochromatin establishment, a comprehensive view of the underlying...
5.
Kanno H, Hiramatsu K, Mikami H, Nakayashiki A, Yamashita S, Nagai A, et al.
Nat Commun . 2024 Sep; 15(1):7376. PMID: 39231964
Flow cytometry is a vital tool in biomedical research and laboratory medicine. However, its accuracy is often compromised by undesired fluctuations in fluorescence intensity. While fluorescence lifetime imaging microscopy (FLIM)...
6.
Braun S
Nat Rev Mol Cell Biol . 2024 Jul; 25(9):676. PMID: 38961267
No abstract available.
7.
Muhammad A, Sarkadi Z, van Emden T, Mazumder A, Capella M, Fekete G, et al.
bioRxiv . 2024 Feb; PMID: 38405799
Heterochromatin plays a critical role in regulating gene expression and maintaining genome integrity. While structural and enzymatic components have been linked to heterochromatin establishment, a comprehensive view of the underlying...
8.
Ozturk M, Freiwald A, Cartano J, Schmitt R, Dejung M, Luck K, et al.
Nat Commun . 2022 Oct; 13(1):6153. PMID: 36257942
Protein abundance is controlled at the transcriptional, translational and post-translational levels, and its regulatory principles are starting to emerge. Investigating these principles requires large-scale proteomics data and cannot just be...
9.
Martin Caballero L, Capella M, Barrales R, Dobrev N, van Emden T, Hirano Y, et al.
Nat Struct Mol Biol . 2022 Sep; 29(9):910-921. PMID: 36123402
Transcriptionally silent chromatin often localizes to the nuclear periphery. However, whether the nuclear envelope (NE) is a site for post-transcriptional gene repression is not well understood. Here we demonstrate that...
10.
Greenstein R, Ng H, Barrales R, Tan C, Braun S, Al-Sady B
PLoS Genet . 2022 May; 18(5):e1010201. PMID: 35584134
Heterochromatin spreading, the expansion of repressive chromatin structure from sequence-specific nucleation sites, is critical for stable gene silencing. Spreading re-establishes gene-poor constitutive heterochromatin across cell cycles but can also invade...