Sigi Benjamin
Overview
Explore the profile of Sigi Benjamin including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
263
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Recent Articles
1.
Khodursky S, Zheng E, Svetec N, Durkin S, Benjamin S, Gadau A, et al.
Genome Biol
. 2023 Oct;
24(1):232.
PMID: 37845780
Background: The evolution of genomic regulatory regions plays a critical role in shaping the diversity of life. While this process is primarily sequence-dependent, the enormous complexity of biological systems complicates...
2.
Khodursky S, Zheng E, Svetec N, Durkin S, Benjamin S, Gadau A, et al.
bioRxiv
. 2023 Jul;
PMID: 37425760
The evolution of regulatory regions in the genome plays a critical role in shaping the diversity of life. While this process is primarily sequence-dependent, the enormous complexity of biological systems...
3.
Witt E, Svetec N, Benjamin S, Zhao L
Mol Biol Evol
. 2021 Jan;
38(5):2104-2115.
PMID: 33481021
Evolutionarily young genes are usually preferentially expressed in the testis across species. Although it is known that older genes are generally more broadly expressed than younger genes, the properties that...
4.
Witt E, Benjamin S, Svetec N, Zhao L
Elife
. 2019 Aug;
8.
PMID: 31418408
The testis is a peculiar tissue in many respects. It shows patterns of rapid gene evolution and provides a hotspot for the origination of genetic novelties such as de novo...
5.
Pekar O, Benjamin S, Weidberg H, Smaldone S, Ramirez F, Horowitz M
Biochem J
. 2012 Mar;
444(3):383-94.
PMID: 22448906
EHD {EH [Eps15 (epidermal growth factor receptor substrate 15) homology]-domain-containing} proteins participate in several endocytic events, such as the internalization and the recycling processes. There are four EHD proteins in...
6.
Benjamin S, Weidberg H, Rapaport D, Pekar O, Nudelman M, Segal D, et al.
Biochem J
. 2011 Jul;
439(3):433-42.
PMID: 21756249
EHDs [EH (Eps15 homology)-domain-containing proteins] participate in different stages of endocytosis. EHD2 is a plasma-membrane-associated EHD which regulates trafficking from the plasma membrane and recycling. EHD2 has a role in...
7.
Bader M, Benjamin S, Wapinski O, Smith D, Goldberg A, Steller H
Cell
. 2011 May;
145(3):371-82.
PMID: 21529711
The ubiquitin-proteasome system catalyzes the degradation of intracellular proteins. Although ubiquitination of proteins determines their stabilities, there is growing evidence that proteasome function is also regulated. We report the functional...
8.
Benjamin S, Steller H
Dev Cell
. 2010 Dec;
19(6):791-2.
PMID: 21145494
Many inhibitor of apoptosis proteins (IAPs) function as E3 ligases to ubiquitinate important cell death proteins, including caspases. Broemer et al. (2010) report recently in Molecular Cell that IAPs can...
9.
Bar M, Benjamin S, Horowitz M, Avni A
Plant Signal Behav
. 2009 Aug;
3(11):1008-10.
PMID: 19704436
Endocytosis regulates many important and diverse processes in eukaryotic life. EH domain containing proteins function as regulators of endocytosis through protein-protein interactions. Several interactors of mammalian EHDs were identified, including...
10.
Olswang-Kutz Y, Gertel Y, Benjamin S, Sela O, Pekar O, Arama E, et al.
J Cell Sci
. 2009 Jan;
122(Pt 4):471-80.
PMID: 19174465
Endocytosis, which is a key process in eukaryotic cells, has a central role in maintaining cellular homeostasis, nutrient uptake, development and downregulation of signal transduction. This complex process depends on...