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Siew Hon Ng

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Recent Articles
1.
Fourie K, Jeffery A, Chand D, Choudhary P, Ng S, Liu H, et al.
Vaccine . 2024 Aug; 42(24):126254. PMID: 39213981
Lawsonia intracellularis is the causative agent of ileitis in swine that manifests as slower weight gain, mild or hemorrhagic diarrhea and/or death in severe cases. As an economically important swine...
2.
Choudhary P, Boamah B, Ng S, White A, Weber L, Wilson H
Vaccine . 2023 May; 41(27):3989-4001. PMID: 37230887
Delayed release of vaccine coupled with a soluble vaccine acts as a primer and a booster with only a single administration, which would be very beneficial to livestock producers. We...
3.
Choudhary P, Khajavinia A, Mohammadi R, Ng S, Berube N, Yalamati D, et al.
Front Vet Sci . 2022 Aug; 9:931232. PMID: 35990278
An effective single-dose vaccine that protects the dam and her suckling offspring against infectious disease would be widely beneficial to livestock animals. We assessed whether a single-dose intramuscular (i.m.) porcine...
4.
Fourie K, Choudhary P, Ng S, Obradovic M, Brownlie R, Anand S, et al.
Vet Immunol Immunopathol . 2021 May; 237:110256. PMID: 33971523
Lawsonia intracellularis is an economically important bacterium that causes ileitis in pigs. Current vaccines for L. intracellularis do not allow for differentiation between infected and vaccinated animals (DIVA), which is...
5.
Haddadi A, Chaffey A, Ng S, Yalamati D, Wilson H
Vaccines (Basel) . 2020 Oct; 8(4). PMID: 33019524
The development of new, effective, and safe vaccines necessarily requires the identification of new adjuvant(s) to enhance the potency and longevity of antigen-specific immune responses. In the present study, we...
6.
Hamonic G, Pasternak J, Ng S, Fourie K, Simko O, Deluco B, et al.
Front Immunol . 2020 Jun; 11:1015. PMID: 32536924
To protect the health of sows and gilts, significant investments are directed toward the development of vaccines against infectious agents that impact reproduction. We developed an intrauterine vaccine that can...
7.
Obradovic M, Pasternak J, Ng S, Allan B, Brownlie R, Wilson H
Vet Microbiol . 2019 Aug; 235:270-279. PMID: 31383312
Lawsonia intracellularis is an obligate intracellular microorganism and the causative agent of porcine proliferative enteropathy. Due to its obligate intracellular nature, characterization of antigens and proteins involved in host-pathogen interaction...
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Thakur S, Obradovic M, Dillon J, Ng S, Wilson H
BMC Microbiol . 2019 Mar; 19(1):67. PMID: 30909866
Background: Neisseria gonorrhoeae is an obligate human pathogen and its adherence to host cells is essential for its pathogenesis. Gonococcal adherence assays are based on the enumeration of bacteria attached...
10.
Obradovic M, Pasternak J, Ng S, Wilson H
J Microbiol Methods . 2016 May; 126:60-6. PMID: 27154728
In this study, we describe a method to quantify invasion of obligate intracellular bacteria, Lawsonia intracellularis, inside McCoy cells. In immunological research, the cell-permeable fluorescent dye 5'-carboxyfluoroscein succidyl ester (CFSE)...