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Siddarth Reddy Karuka

Explore the profile of Siddarth Reddy Karuka including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 19
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Recent Articles
1.
Angert I, Karuka S, Mansky L, Mueller J
Sci Adv . 2022 Aug; 8(33):eabj3236. PMID: 35984883
The cell cortex plays a crucial role in cell mechanics, signaling, and development. However, little is known about the influence of the cortical meshwork on the spatial distribution of cytoplasmic...
2.
Hennen J, Kohler J, Karuka S, Saunders C, Luxton G, Mueller J
Biophys J . 2020 Apr; 118(10):2385-2399. PMID: 32304637
The nuclear envelope (NE) consists of two concentric nuclear membranes separated by the lumen, an ∼40-nm-wide fluid layer. NE proteins are implicated in important cellular processes ranging from gene expression...
3.
Karuka S, Hennen J, Hur K, Mueller J
Data Brief . 2020 Apr; 28:105005. PMID: 32226805
Fluorescence fluctuation microscopy is a widely used method to determine the mobility and oligomeric state of proteins in the live cell environment. Existing analysis methods rely on statistical evaluation of...
4.
Angert I, Karuka S, Hennen J, Chen Y, Albanesi J, Mansky L, et al.
Biophys J . 2019 Dec; 118(2):281-293. PMID: 31870539
Delicate and transitory protein engagement at the plasma membrane (PM) is crucial to a broad range of cellular functions, including cell motility, signal transduction, and virus replication. Here, we describe...
5.
Hennen J, Hur K, Kohler J, Karuka S, Angert I, Luxton G, et al.
Biophys J . 2019 Dec; 118(1):26-35. PMID: 31839257
The nucleus is delineated by the nuclear envelope (NE), which is a double membrane barrier composed of the inner and outer nuclear membranes as well as a ∼40-nm wide lumen....
6.
Hennen J, Hur K, Karuka S, Luxton G, Mueller J
Methods . 2018 Oct; 157:28-41. PMID: 30268407
Analysis of fluorescence fluctuation experiments by the mean-segmented Q (MSQ) method was recently used to successfully characterize the oligomeric state and mobility of proteins within the nuclear envelope (NE) of...