Siddappa N Byrareddy
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Explore the profile of Siddappa N Byrareddy including associated specialties, affiliations and a list of published articles.
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161
Citations
4645
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Recent Articles
1.
Pandey K, Lewis D, Heo K, Acharya A, Fields T, Gowda K, et al.
Sci Rep
. 2025 Feb;
15(1):5671.
PMID: 39955340
The 3-chymotrypsin-like protease (3CLpro), papain-like protease (PLpro), and RNA-dependent RNA polymerase (RdRp) are key enzymes in SARS-CoV-2 replication and serve as critical targets for an antiviral drug. Currently, Paxlovid® and...
2.
Johnson S, Pino M, Acharya A, Clain J, Bose D, Nguyen K, et al.
JCI Insight
. 2025 Feb;
PMID: 39903521
Despite combination antiretroviral therapy (ART), HIV causes persistent gut barrier dysfunction, immune depletion, and dysbiosis. Further, ART interruption results in reservoir reactivation and rebound viremia. Both IL-21 and anti-α4β7 improve...
3.
Selvavinayagam S, Sankar S, Yong Y, Anshad A, Chandramathi S, Somasundaram A, et al.
PLOS Glob Public Health
. 2024 Dec;
4(12):e0004157.
PMID: 39739977
[This corrects the article DOI: 10.1371/journal.pgph.0003608.].
4.
Gaikwad M, George A, Sivadas A, Karunakaran K, N S, Byrareddy S, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2024 Dec;
PMID: 39636407
No abstract available.
5.
Selvavinayagam S, Sankar S, Yong Y, Anshad A, Chandramathi S, Somasundaram A, et al.
PLOS Glob Public Health
. 2024 Nov;
4(11):e0003608.
PMID: 39570962
The decline in dengue incidence and/or prevalence during the COVID-19 pandemic (2020-22) appears to be attributed to reduced treatment-seeking rates, under-reporting, misdiagnosis, disrupted health services and reduced exposure to mosquito...
6.
Kaur Sardarni U, Ambikan A, Acharya A, Johnson S, Avedissian S, Vegvari A, et al.
Brain Behav Immun
. 2024 Oct;
123:914-927.
PMID: 39481495
Despite significant effort, a clear understanding of host tissue-specific responses and their implications for immunopathogenicity against the severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) variant infection has remained poorly defined. To...
7.
Poli A, Tietjen I, Nandwana N, Cassel J, Messick T, Register E, et al.
Antimicrob Agents Chemother
. 2024 Sep;
68(10):e0056224.
PMID: 39225484
We have synthesized a novel and highly selective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease peptide mimetic inhibitor mimicking the replicase 1ab recognition sequence -Val-Leu-Gln- and utilizing a...
8.
Rajaiah R, Pandey K, Acharya A, Ambikan A, Kumar N, Guda R, et al.
iScience
. 2024 Aug;
27(8):110501.
PMID: 39171289
Delta (B.1.617.2) and Omicron (B.1.1.529) variants of SARS-CoV-2 represents unique clinical characteristics. However, their role in altering immunometabolic regulations during acute infection remains convoluted. Here, we evaluated the differential immunopathogenesis...
9.
Selvavinayagam S, Sankar S, Yong Y, Murugesan A, Suvaithenamudhan S, Hemashree K, et al.
Sci Rep
. 2024 Jul;
14(1):17476.
PMID: 39080396
In December 2023, we observed a notable shift in the COVID-19 landscape, when JN.1 omicron emerged as the predominant SARS-CoV-2 variant with a 95% incidence. We characterized the clinical profile,...
10.
Pathania A, Chava H, Chaturvedi N, Chava S, Byrareddy S, Coulter D, et al.
Cell Death Dis
. 2024 Jun;
15(6):428.
PMID: 38890285
Neuroblastoma (NB) is a highly aggressive pediatric cancer that originates from immature nerve cells, presenting significant treatment challenges due to therapy resistance. Despite intensive treatment, approximately 50% of high-risk NB...