Sian R Kitcher
Overview
Explore the profile of Sian R Kitcher including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
100
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Co-release of GABA and ACh from medial olivocochlear neurons fine tunes cochlear efferent inhibition
Castagnola T, Castagna V, Kitcher S, Torres Cadenas L, Di Guilmi M, Gomez Casati M, et al.
bioRxiv
. 2024 Aug;
PMID: 39185230
During development, inner hair cells (IHCs) in the mammalian cochlea are unresponsive to acoustic stimuli but instead exhibit spontaneous activity. During this same period, neurons originating from the medial olivocochlear...
2.
Buswinka C, Rosenberg D, Simikyan R, Osgood R, Fernandez K, Nitta H, et al.
Sci Data
. 2024 Apr;
11(1):416.
PMID: 38653806
Our sense of hearing is mediated by cochlear hair cells, of which there are two types organized in one row of inner hair cells and three rows of outer hair...
3.
Bachman J, Kitcher S, Vattino L, Beaulac H, Chaves M, Rivera I, et al.
bioRxiv
. 2024 Apr;
PMID: 38586043
Cochlear outer hair cells (OHCs) are electromotile and are implicated in mechanisms of amplification of responses to sound that enhance sound sensitivity and frequency tuning. They send information to the...
4.
Derudas M, OReilly M, Kirkwood N, Kenyon E, Grimsey S, Kitcher S, et al.
Front Cell Dev Biol
. 2023 Oct;
11:1247324.
PMID: 37900280
The styryl dye FM1-43 is widely used to study endocytosis but behaves as a permeant blocker of the mechano-electrical transducer (MET) channel in sensory hair cells, loading rapidly and specifically...
5.
Buswinka C, Rosenberg D, Simikyan R, Osgood R, Fernandez K, Nitta H, et al.
bioRxiv
. 2023 Sep;
PMID: 37693382
Our sense of hearing is mediated by cochlear hair cells, localized within the sensory epithelium called the organ of Corti. There are two types of hair cells in the cochlea,...
6.
Kitcher S, Pederson A, Weisz C
Hear Res
. 2021 Jun;
419:108278.
PMID: 34108087
Accurate encoding of acoustic stimuli requires temporally precise responses to sound integrated with cellular mechanisms that encode the complexity of stimuli over varying timescales and orders of magnitude of intensity....
7.
Kenyon E, Kirkwood N, Kitcher S, Goodyear R, Derudas M, Cantillon D, et al.
JCI Insight
. 2021 Mar;
6(7).
PMID: 33735112
To identify small molecules that shield mammalian sensory hair cells from the ototoxic side effects of aminoglycoside antibiotics, 10,240 compounds were initially screened in zebrafish larvae, selecting for those that...
8.
Kitcher S, Weisz C
EMBO Mol Med
. 2020 Jul;
12(8):e12620.
PMID: 32715629
Electrical cochlear implants (CI) currently lack the frequency and intensity resolution to allow detection of complex sounds in background noise. The use of microscale optoelectronics in conjunction with optogenetics provides...
9.
Kitcher S, Kirkwood N, Camci E, Wu P, Gibson R, Redila V, et al.
JCI Insight
. 2019 Aug;
4(15).
PMID: 31391343
Aminoglycoside (AG) antibiotics are widely used to prevent life-threatening infections, and cisplatin is used in the treatment of various cancers, but both are ototoxic and result in loss of sensory...
10.
Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death
Kenyon E, Kirkwood N, Kitcher S, OReilly M, Derudas M, Cantillon D, et al.
JCI Insight
. 2017 Dec;
2(24).
PMID: 29263311
Aminoglycoside antibiotics are used to treat life-threatening bacterial infections but can cause deafness due to hair cell death in the inner ear. Compounds have been described that protect zebrafish lateral...