Richard T Osgood
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Explore the profile of Richard T Osgood including associated specialties, affiliations and a list of published articles.
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8
Citations
38
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Recent Articles
1.
Strelkova O, Osgood R, Tian C, Zhang X, Hale E, De-la-Torre P, et al.
Commun Biol
. 2024 Nov;
7(1):1423.
PMID: 39482437
Polycystic Kidney and Hepatic Disease 1-Like 1 (PKHD1L1) is a human deafness gene, responsible for autosomal recessive deafness-124 (DFNB124). Sensory hair cells of the cochlea are essential for hearing, relying...
2.
Buswinka C, Rosenberg D, Simikyan R, Osgood R, Fernandez K, Nitta H, et al.
Sci Data
. 2024 Apr;
11(1):416.
PMID: 38653806
Our sense of hearing is mediated by cochlear hair cells, of which there are two types organized in one row of inner hair cells and three rows of outer hair...
3.
Strelkova O, Osgood R, Tian C, Zhang X, Hale E, De-la-Torre P, et al.
bioRxiv
. 2024 Mar;
PMID: 38496629
Sensory hair cells of the cochlea are essential for hearing, relying on the mechanosensitive stereocilia bundle at their apical pole for their function. Polycystic Kidney and Hepatic Disease 1-Like 1...
4.
Buswinka C, Rosenberg D, Simikyan R, Osgood R, Fernandez K, Nitta H, et al.
bioRxiv
. 2023 Sep;
PMID: 37693382
Our sense of hearing is mediated by cochlear hair cells, localized within the sensory epithelium called the organ of Corti. There are two types of hair cells in the cochlea,...
5.
Buswinka C, Nitta H, Osgood R, Indzhykulian A
bioRxiv
. 2023 May;
PMID: 37214838
The segmentation of individual instances of mitochondria from imaging datasets is informative, yet time-consuming to do by hand, sparking interest in developing automated algorithms using deep neural networks. Existing solutions...
6.
Buswinka C, Osgood R, Simikyan R, Rosenberg D, Indzhykulian A
PLoS Biol
. 2023 Mar;
21(3):e3002041.
PMID: 36947567
Our sense of hearing is mediated by sensory hair cells, precisely arranged and highly specialized cells subdivided into outer hair cells (OHCs) and inner hair cells (IHCs). Light microscopy tools...
7.
Kenyon E, Kirkwood N, Kitcher S, Goodyear R, Derudas M, Cantillon D, et al.
JCI Insight
. 2021 Mar;
6(7).
PMID: 33735112
To identify small molecules that shield mammalian sensory hair cells from the ototoxic side effects of aminoglycoside antibiotics, 10,240 compounds were initially screened in zebrafish larvae, selecting for those that...
8.
Goodyear R, Cheatham M, Naskar S, Zhou Y, Osgood R, Zheng J, et al.
Front Mol Neurosci
. 2019 Jun;
12:147.
PMID: 31249509
CEACAM16 is a non-collagenous protein of the tectorial membrane, an extracellular structure of the cochlea essential for normal hearing. Dominant and recessive mutations in have been reported to cause postlingual...