Sian Megan Joanna Hemmings
Overview
Explore the profile of Sian Megan Joanna Hemmings including associated specialties, affiliations and a list of published articles.
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16
Citations
166
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Recent Articles
1.
Ngala M, Hemmings S, Womersley J, Shabangu T, Qulu-Appiah L
BMC Neurosci
. 2025 Feb;
26(1):15.
PMID: 40011829
Background: Sexual violence, a pervasive global issue, significantly impacts individuals and societies, necessitating a deeper understanding of its underlying biological mechanisms. This study aimed to elucidate the role of stress-induced...
2.
van Rensburg D, Womersley J, Martin L, Seedat S, Hemmings S
Eur J Neurosci
. 2024 Aug;
60(7):5680-5693.
PMID: 39189635
Biological mechanisms underlying anxiety proneness (AP), the tendency to react fearfully to stressors due to the belief that experiencing anxiety has harmful consequences, remain unclear. Epigenetic mechanisms, such as microRNAs...
3.
Mbiydzenyuy N, Hemmings S, Shabangu T, Qulu-Appiah L
Heliyon
. 2024 Mar;
10(5):e27501.
PMID: 38486749
Stress is a complex and multifaceted phenomenon that can significantly influence both aggressive behavior and sexual function. This review explores the intricate relationship between stress, neuromodulator pathways, and epigenetics, shedding...
4.
Mbiydzenyuy N, Hemmings S, Qulu L
Front Behav Neurosci
. 2022 Oct;
16:977416.
PMID: 36212196
Even though studies have shown that prenatal maternal stress is associated with increased reactivity of the HPA axis, the association between prenatal maternal stress and fetal glucocorticoid exposure is complex...
5.
Roomaney A, Womersley J, Swart P, Spies G, Seedat S, Hemmings S
IBRO Neurosci Rep
. 2022 Jun;
12:45-54.
PMID: 35746967
HIV/AIDS is a major public health burden in South Africa, currently affecting an estimated 13.5% of the population. Despite improved access to antiretroviral therapies, HIV-associated neurocognitive disorders (HAND), characterised by...
6.
Nothling J, Abrahams N, Jewkes R, Mhlongo S, Lombard C, Hemmings S, et al.
J Affect Disord
. 2022 Apr;
309:151-164.
PMID: 35427719
Introduction: The prevalence of posttraumatic stress disorder (PTSD) in rape survivors is considerably higher than the prevalence in non-sexual trauma survivors. Few studies have investigated risk and protective factors in...
7.
Nothling J, Abrahams N, Toikumo S, Suderman M, Mhlongo S, Lombard C, et al.
Transl Psychiatry
. 2021 Nov;
11(1):594.
PMID: 34799556
Rape is associated with a high risk for posttraumatic stress disorder (PTSD). DNA methylation changes may confer risk or protection for PTSD following rape by regulating the expression of genes...
8.
Womersley J, Spies G, Tromp G, Seedat S, Hemmings S
J Neurovirol
. 2021 Aug;
27(5):735-749.
PMID: 34448146
HIV-associated neurocognitive disorders (HAND) present a challenge in South Africa where the burden of HIV infection is the highest. Identification of biological correlates of HAND is required to improve diagnosis...
9.
Genetic variation in neuropeptide Y interacts with childhood trauma to influence anxiety sensitivity
Womersley J, Martin L, van der Merwe L, Seedat S, Hemmings S
Anxiety Stress Coping
. 2021 Jan;
34(4):450-464.
PMID: 33491492
Background And Objectives: Anxiety sensitivity (AS) refers to a fear of the negative implications of anxiety, and arises due to gene-environment interactions. We investigated whether genetic variation in two neuropeptides...
10.
Nothling J, Malan-Muller S, Abrahams N, Hemmings S, Seedat S
World J Biol Psychiatry
. 2019 Feb;
21(7):493-512.
PMID: 30806160
Multiple, chronic and repeated trauma exposure in childhood is associated with adverse mental health outcomes in adulthood. In this paper we synthesise the literature on epigenetic modifications in childhood trauma...