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Si-Lin Koo

Explore the profile of Si-Lin Koo including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 1516
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Recent Articles
11.
Simoni Y, Becht E, Fehlings M, Loh C, Koo S, Teng K, et al.
Nature . 2018 May; 557(7706):575-579. PMID: 29769722
Various forms of immunotherapy, such as checkpoint blockade immunotherapy, are proving to be effective at restoring T cell-mediated immune responses that can lead to marked and sustained clinical responses, but...
12.
Simoni Y, Fehlings M, Kloverpris H, McGovern N, Koo S, Loh C, et al.
Immunity . 2018 May; 48(5):1060. PMID: 29768165
No abstract available.
13.
Ng T, Dorajoo S, Cheung Y, Lam Y, Yeo H, Shwe M, et al.
Psychooncology . 2018 Jan; 27(4):1185-1192. PMID: 29315963
Objectives: Currently, there are no studies that have established the self-perceived cognitive trajectories experienced by breast cancer patients (BCPs) post-chemotherapy. Therefore, we characterized the long-term trajectory of self-perceived cognitive function...
14.
Chae J, Chua P, Ng T, Yeo A, Shwe M, Gan Y, et al.
Breast Cancer Res Treat . 2018 Jan; 168(3):713-721. PMID: 29313215
Purpose: Cancer-related fatigue (CRF) and chemotherapy-related cognitive impairment (CRCI) are reported to be associated with mitochondrial dysfunction. Hence, mitochondrial DNA (mtDNA) content, a biomarker of mitochondrial dysfunction, is hypothesized to...
15.
Ng S, Chua C, Ng M, Gan A, Poon P, Teo M, et al.
Sci Rep . 2017 Jan; 7:40737. PMID: 28102343
Circulating tumour DNA (ctDNA) has the potential to be a specific biomarker for the monitoring of tumours in patients with colorectal cancer (CRC). Here, our aim was to develop a...
16.
Simoni Y, Fehlings M, Kloverpris H, McGovern N, Koo S, Loh C, et al.
Immunity . 2016 Dec; 46(1):148-161. PMID: 27986455
Animal models have highlighted the importance of innate lymphoid cells (ILCs) in multiple immune responses. However, technical limitations have hampered adequate characterization of ILCs in humans. Here, we used mass...
17.
Matsumoto H, Thike A, Li H, Yeong J, Koo S, Dent R, et al.
Breast Cancer Res Treat . 2016 Mar; 156(2):237-47. PMID: 26960711
Tumour-infiltrating lymphocytes (TILs) signify immune response to tumour in a variety of cancers including breast cancer. However, earlier studies examining the clinical significance of TILs in breast cancers have generated...
18.
Adusumalli S, Lee H, Hoi Q, Koo S, Tan I, Ng P
J Med Internet Res . 2015 Aug; 17(8):e211. PMID: 26319108
Background: Some health websites provide a public forum for consumers to post ratings and reviews on drugs. Drug reviews are easily accessible and comprehensible, unlike clinical trials and published literature....
19.
Ng T, Teo S, Yeo H, Shwe M, Gan Y, Cheung Y, et al.
Neuro Oncol . 2015 Aug; 18(2):244-51. PMID: 26289590
Background: Brain-derived neurotrophic factor (BDNF), a neurotrophin that regulates neuronal function and development, is implicated in several neurodegenerative conditions. Preliminary data suggest that a reduction of BDNF concentrations may lead...
20.
Matsumoto H, Koo S, Dent R, Tan P, Iqbal J
J Clin Pathol . 2015 Mar; 68(7):506-10. PMID: 25750267
Triple negative breast cancer (TNBC) is a heterogenous disease often characterised by aggressive biology and poor prognosis. Efforts to precisely treat TNBC have been compounded by the lack of specific...