Si-Houy Lao-Sirieix
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Explore the profile of Si-Houy Lao-Sirieix including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
124
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Recent Articles
1.
Meyer T, Qian W, Caplin M, Armstrong G, Lao-Sirieix S, Hardy R, et al.
Eur J Cancer
. 2014 Jan;
50(5):902-11.
PMID: 24445147
Background: Cytotoxic chemotherapy is widely used for advanced, unresectable pancreatic and other gastrointestinal foregut neuroendocrine tumours (NETs) and the most commonly used regimen combines 5-fluorouracil with streptozocin. The NET01 trial...
2.
Lao-Sirieix S, Nookala R, Roversi P, Bell S, Pellegrini L
Nat Struct Mol Biol
. 2005 Nov;
12(12):1137-44.
PMID: 16273105
Primases are DNA-dependent RNA polymerases that synthesize the oligoribonucleotide primers essential to DNA replication. In archaeal and eukaryotic organisms, the core primase is a heterodimeric enzyme composed of a small...
3.
Lao-Sirieix S, Pellegrini L, Bell S
Trends Genet
. 2005 Aug;
21(10):568-72.
PMID: 16095750
DNA primases are essential for the initiation of DNA replication and progression of the replication fork. Recent phylogenetic analyses coupled with biochemical and structural studies have revealed that the arrangement...
4.
Lao-Sirieix S, Bell S
J Mol Biol
. 2004 Nov;
344(5):1251-63.
PMID: 15561142
A eukaryotic-type primase was identified in the crenarchaeon Sulfolobus solfataricus. The two-subunit DNA-dependent primase, termed PriSL, was purified following co-expression of the subunits in Escherichia coli and its activity was...