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Shumin Deng

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Articles 31
Citations 235
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Recent Articles
1.
Cheng C, Zha Q, Sun L, Cui T, Guo X, Xing C, et al.
Signal Transduct Target Ther . 2025 Jan; 10(1):26. PMID: 39848960
CD8T cells within the tumor microenvironment (TME) are often functionally impaired, which limits their ability to mount effective anti-tumor responses. However, the molecular mechanisms behind this dysfunction remain incompletely understood....
2.
Guo X, Cui T, Sun L, Fu Y, Cheng C, Wu C, et al.
Cell Death Differ . 2024 Dec; PMID: 39690246
Hepatocellular carcinoma (HCC) is a malignant tumor characterized by rapid progression. To explore the regulatory mechanism of rapid tumor growth and metastasis, we conducted proteomic and scRNA-Seq analyses on advanced...
3.
Qiu L, Lu X, Xue W, Fu H, Deng S, Li L, et al.
Gene . 2024 Oct; 934:149017. PMID: 39437898
Objectives: Ischemic stroke (IS) prevalence rising annually, the necessity of discovering non-interventional genetic influences is progressing. Single nucleotide polymorphism (SNP) plays a pivotal role in stable inheritance of disease susceptibility....
4.
Deng S, Li H, Zuo W, Liu Z, Wu Y
BMJ Open . 2024 Sep; 14(9):e082717. PMID: 39299789
Objectives: This study aims to calculate the national prevalence of smoking among Chinese adults and to describe the hazard of smoking initiation by age during their adolescence, as well as...
5.
Lu P, Deng S, Liu J, Xiao Q, Zhou Z, Li S, et al.
MedComm (2020) . 2024 Jun; 5(6):e576. PMID: 38827027
Colorectal cancer (CRC) is one of the leading cancers worldwide, with metastasis being a major cause of high mortality rates among patients. In this study, dysregulated gene Tweety homolog 3...
6.
Xie S, Chen M, Qiu L, Li L, Deng S, Liu F, et al.
J Immunol Res . 2023 Dec; 2023:6616822. PMID: 38089115
Methods: A multivariate predictive nomogram model was developed using the risk factors identified by LASSO regression and assessed by receiver operator characteristics (ROC) curve, calibration curve, and decision curve analysis....
7.
Qiu L, Wang Y, Wang Y, Liu F, Deng S, Xue W, et al.
Drug Des Devel Ther . 2023 Aug; 17:2481-2493. PMID: 37637267
Purpose: The oxygen and glucose deprivation-reoxygenation (OGDR) model is widely used to evaluate ischemic stroke and cerebral ischemia-reperfusion (I/R) injury in vitro. Excessively activated microglia produce pro-inflammatory mediators such as...
8.
Zhang D, Zhang W, Deng S, Liu L, Wei H, Xue F, et al.
Biomed Pharmacother . 2023 Aug; 165:115259. PMID: 37531785
Sleep disturbances are commonly non-motor symptoms in Parkinson's diseases (PD). However, standard dopamine replacement therapies for the treatment of motor symptoms often prove inadequate in combating sleep disturbances. Previous studies...
9.
Qiu L, Li L, He Z, Liu F, Deng S, Wang Y
Am J Transl Res . 2023 Jun; 15(5):3326-3341. PMID: 37303653
Objectives: Ischemic stroke has long been a global health threat. Genetic factors, a looming risk for ischemic stroke, remain unexplored. The high-mobility group box 1 (HMGB1) protein showed a connection...
10.
Qiu L, Wang Y, Liu F, Deng S, He Z, Zheng W, et al.
J Int Med Res . 2023 May; 51(5):3000605231173578. PMID: 37170751
Objective: The incidence of stroke has been rising annually and investigations into traditional risk factors have led to increased attention on genetic factors. In this study, we focused on the...