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Shuji Kanamaru

Explore the profile of Shuji Kanamaru including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 950
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Recent Articles
1.
Munetomo S, Uchiyama J, Takemura-Uchiyama I, Wanganuttara T, Yamamoto Y, Tsukui T, et al.
PLoS One . 2024 Oct; 19(10):e0310962. PMID: 39441843
Methicillin-resistant Staphylococcus spp. present challenges in clinical and veterinary settings because effective antimicrobial agents are limited. Phage-encoded peptidoglycan-degrading enzyme, endolysin, is expected to be a novel antimicrobial agent. The enzymatic...
2.
Ito K, Maki T, Kanamaru S, Takahashi M, Iwasaki H
Nucleic Acids Res . 2024 Sep; 52(20):12517-12533. PMID: 39340300
In eukaryotes, Dmc1 and Rad51 are key proteins of homologous recombination. The Swi5-Sfr1 complex in fission yeast, a conserved auxiliary factor, stimulates DNA strand exchange driven by both Dmc1 and...
3.
Zhu B, Nosaka N, Kanamaru S, Dong J, Dai Y, Inoue A, et al.
Analyst . 2022 Oct; 147(22):4971-4979. PMID: 36205380
Antigen tests for SARS-CoV-2 are widely used by the public during the ongoing COVID-19 pandemic, which demonstrates the societal impact of homogeneous immunosensor-related technologies. In this study, we used the...
4.
Abe S, Tanaka J, Kojima M, Kanamaru S, Hirata K, Yamashita K, et al.
Sci Rep . 2022 Oct; 12(1):16031. PMID: 36192567
In-cell protein crystallization (ICPC) has been investigated as a technique to support the advancement of structural biology because it does not require protein purification and a complicated crystallization process. However,...
5.
Takemura-Uchiyama I, Tsurui H, Shimakura H, Nasukawa T, Imanishi I, Uchiyama J, et al.
FEMS Microbiol Lett . 2022 Feb; 369(1). PMID: 35191469
Staphylococcus pseudintermedius is one of the major pathogens causing canine skin infection. In canine atopic dermatitis (AD), heterogeneous strains of S. pseudintermedius reside on the affected skin site. Because an...
6.
Zdravkovic A, Daley J, Dutta A, Niwa T, Murayama Y, Kanamaru S, et al.
Proc Natl Acad Sci U S A . 2021 Apr; 118(11). PMID: 33836577
The Mre11-Rad50-Nbs1 complex (MRN) is important for repairing DNA double-strand breaks (DSBs) by homologous recombination (HR). The endonuclease activity of MRN is critical for resecting 5'-ended DNA strands at DSB...
7.
Kanamaru S, Uchida K, Nemoto M, Fraser A, Arisaka F, Leiman P
Viruses . 2020 Sep; 12(10). PMID: 32987925
The bacteriophage T4 genome contains two genes that code for proteins with lysozyme activity- and . Gene encodes the well-known T4 lysozyme (commonly called T4L) that functions to break the...
8.
Ito K, Murayama Y, Kurokawa Y, Kanamaru S, Kokabu Y, Maki T, et al.
Nat Commun . 2020 Jun; 11(1):2950. PMID: 32528002
During homologous recombination, Rad51 forms a nucleoprotein filament on single-stranded DNA to promote DNA strand exchange. This filament binds to double-stranded DNA (dsDNA), searches for homology, and promotes transfer of...
9.
Argunhan B, Sakakura M, Afshar N, Kurihara M, Ito K, Maki T, et al.
Elife . 2020 Mar; 9. PMID: 32204793
Although Rad51 is the key protein in homologous recombination (HR), a major DNA double-strand break repair pathway, several auxiliary factors interact with Rad51 to promote productive HR. We present an...
10.
Kim R, Kanamaru S, Mikawa T, Prevost C, Ishii K, Ito K, et al.
Nucleic Acids Res . 2018 Feb; 46(5):2548-2559. PMID: 29390145
Mg2+ ion stimulates the DNA strand exchange reaction catalyzed by RecA, a key step in homologous recombination. To elucidate the molecular mechanisms underlying the role of Mg2+ and the strand...