Michael G Rossmann
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Explore the profile of Michael G Rossmann including associated specialties, affiliations and a list of published articles.
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218
Citations
12956
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Recent Articles
1.
Olson N, Kolatkar P, Oliveira M, Cheng R, Greve J, McClelland A, et al.
Protein Eng
. 2024 Apr;
6(Suppl):1.
PMID: 38626270
No abstract available.
2.
Wang Z, Fokine A, Guo X, Jiang W, Rossmann M, Kuhn R, et al.
Viruses
. 2023 Aug;
15(8).
PMID: 37632015
Antibiotic resistance poses a growing risk to public health, requiring new tools to combat pathogenic bacteria. Contractile injection systems, including bacteriophage tails, pyocins, and bacterial type VI secretion systems, can...
3.
Shao Q, Agarkova I, Noel E, Dunigan D, Liu Y, Wang A, et al.
Nat Commun
. 2022 Oct;
13(1):6476.
PMID: 36309542
Giant viruses are a large group of viruses that infect many eukaryotes. Although components that do not obey the overall icosahedral symmetry of their capsids have been observed and found...
4.
Fang Q, Tang W, Fokine A, Mahalingam M, Shao Q, Rossmann M, et al.
Proc Natl Acad Sci U S A
. 2022 Sep;
119(40):e2203272119.
PMID: 36161892
Many icosahedral viruses assemble proteinaceous precursors called proheads or procapsids. Proheads are metastable structures that undergo a profound structural transition known as expansion that transforms an immature unexpanded head into...
5.
Chen C, Klose T, Sun C, Kim A, Buda G, Rossmann M, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(30):e2114119119.
PMID: 35867819
Alphaviruses can cause severe human arthritis and encephalitis. During virus infection, structural changes of viral glycoproteins in the acidified endosome trigger virus-host membrane fusion for delivery of the capsid core...
6.
Khare B, Klose T, Fang Q, Rossmann M, Kuhn R
Proc Natl Acad Sci U S A
. 2021 Aug;
118(34).
PMID: 34417300
Usutu virus (USUV) is an emerging arbovirus in Europe that has been increasingly identified in asymptomatic humans and donated blood samples and is a cause of increased incidents of neuroinvasive...
7.
Sevvana M, Rogers T, Miller A, Long F, Klose T, Beutler N, et al.
Viruses
. 2020 Dec;
12(12).
PMID: 33255202
Zika virus (ZIKV), a mosquito-borne human flavivirus that causes microcephaly and other neurological disorders, has been a recent focus for the development of flavivirus vaccines and therapeutics. We report here...
8.
Powell L, Miller A, Fox J, Kose N, Klose T, Kim A, et al.
Cell Host Microbe
. 2020 Aug;
28(5):699-711.e7.
PMID: 32783883
Mosquito inoculation of humans with arthritogenic alphaviruses results in a febrile syndrome characterized by debilitating musculoskeletal pain and arthritis. Despite an expanding global disease burden, no approved therapies or licensed...
9.
Vogt M, Fu J, Kose N, Williamson L, Bombardi R, Setliff I, et al.
Sci Immunol
. 2020 Jul;
5(49).
PMID: 32620559
Enterovirus D68 (EV-D68) causes outbreaks of respiratory illness, and there is increasing evidence that it causes outbreaks of acute flaccid myelitis (AFM). There are no licensed therapies to prevent or...
10.
Fang Q, Tang W, Tao P, Mahalingam M, Fokine A, Rossmann M, et al.
Nat Commun
. 2020 Apr;
11(1):1713.
PMID: 32249784
Large biological structures are assembled from smaller, often symmetric, sub-structures. However, asymmetry among sub-structures is fundamentally important for biological function. An extreme form of asymmetry, a 12-fold-symmetric dodecameric portal complex...