Shuichi Kani
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Explore the profile of Shuichi Kani including associated specialties, affiliations and a list of published articles.
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11
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1110
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Recent Articles
1.
Kim J, Park K, Ishida J, Kako K, Hamada J, Kani S, et al.
Sci Adv
. 2015 Dec;
1(11):e1500615.
PMID: 26665171
The development of vertebrate neurons requires a change in membrane phosphatidylcholine (PC) metabolism. Although PC hydrolysis is essential for enhanced axonal outgrowth mediated by phospholipase D (PLD), less is known...
2.
Maeda K, Kobayashi Y, Udagawa N, Uehara S, Ishihara A, Mizoguchi T, et al.
Nat Med
. 2012 Feb;
18(3):405-12.
PMID: 22344299
The signaling molecule Wnt regulates bone homeostasis through β-catenin-dependent canonical and β-catenin-independent noncanonical pathways. Impairment of canonical Wnt signaling causes bone loss in arthritis and osteoporosis; however, it is unclear...
3.
Tanabe K, Kani S, Shimizu T, Bae Y, Abe T, Hibi M
J Neurosci
. 2010 Dec;
30(50):16983-92.
PMID: 21159968
Neurons have highly polarized structures that determine what parts of the soma elaborate the axon and dendrites. However, little is known about the mechanisms that establish neuronal polarity in vivo....
4.
Shimizu T, Nakazawa M, Kani S, Bae Y, Shimizu T, Kageyama R, et al.
Development
. 2010 May;
137(11):1875-85.
PMID: 20431123
Precise control of neuronal differentiation is necessary for generation of a variety of neurons in the forebrain. However, little is known about transcriptional cascades, which initiate forebrain neurogenesis. Here we...
5.
Kani S, Bae Y, Shimizu T, Tanabe K, Satou C, Parsons M, et al.
Dev Biol
. 2010 Apr;
343(1-2):1-17.
PMID: 20388506
In mammals, cerebellar neurons are categorized as glutamatergic or GABAergic, and are derived from progenitors that express the proneural genes atoh1 or ptf1a, respectively. In zebrafish, three atoh1 genes, atoh1a,...
6.
Bae Y, Kani S, Shimizu T, Tanabe K, Nojima H, Kimura Y, et al.
Dev Biol
. 2009 Apr;
330(2):406-26.
PMID: 19371731
The cerebellum is important for the integration of sensory perception and motor control, but its structure has mostly been studied in mammals. Here, we describe the cell types and neural...
7.
Kani S, Nakayama E, Yoda A, Onishi N, Sougawa N, Hazaka Y, et al.
Genes Cells
. 2007 Aug;
12(8):919-28.
PMID: 17663721
Methylglyoxal (MG) is a reactive endogenous metabolite that is produced from the process of degradation of triose-phosphates. Under hyperglycemic conditions the rate of MG formation increases as a result of...
8.
Nishita M, Yoo S, Nomachi A, Kani S, Sougawa N, Ohta Y, et al.
J Cell Biol
. 2006 Nov;
175(4):555-62.
PMID: 17101698
The receptor tyrosine kinase Ror2 plays important roles in developmental morphogenesis. It has recently been shown that Ror2 mediates Wnt5a-induced noncanonical Wnt signaling by activating the Wnt-JNK pathway and inhibiting...
9.
Kani S, Oishi I, Yamamoto H, Yoda A, Suzuki H, Nomachi A, et al.
J Biol Chem
. 2004 Sep;
279(48):50102-9.
PMID: 15375164
Ror2, a member of the mammalian Ror family of receptor tyrosine kinases, plays important roles in developmental morphogenesis, although the mechanism underlying activation of Ror2 remains largely elusive. We show...
10.
Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B, et al.
Genes Cells
. 2003 Jul;
8(7):645-54.
PMID: 12839624
Background: Ror2 is an orphan receptor, belonging to the Ror family of receptor tyrosine kinases. Although Ror2 has been shown to play crucial roles in developmental morphogenesis, the precise signalling...