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Shu-Yu Lin

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Articles 94
Citations 1339
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Recent Articles
11.
Lin S, Chiang M, Wu W, Wu I, Lai M, Chu S, et al.
Pediatr Neonatol . 2023 Dec; 65(4):375-380. PMID: 38114415
No abstract available.
12.
Singh S, Yeat N, Wang Y, Lin S, Kuo I, Wu K, et al.
Cell Death Dis . 2023 Oct; 14(10):671. PMID: 37821451
Aberrant overexpression or activation of EGFR drives the development of non-small cell lung cancer (NSCLC) and acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) by secondary EGFR mutations or c-MET...
13.
Chen C, Tsai C, Lin M, Lin S, Hsu C
Anal Chem . 2023 Aug; 95(33):12232-12239. PMID: 37552764
Plant phosphoproteomics provides a global view of phosphorylation-mediated signaling in plants; however, it demands high-throughput methods with sensitive detection and accurate quantification. Despite the widespread use of protein precipitation for...
14.
Lin S, Chou S, Tseng C, Wu Y
Spectrochim Acta A Mol Biomol Spectrosc . 2023 Jul; 302:123060. PMID: 37399612
We employ electron bombardment during the deposition of an Ar matrix containing a small proportion of SiH to generate various silicon hydrides. Subsequently, the irradiation of a matrix sample at...
15.
Chang Y, Lin S, Kang Z, Shen B, Tsai W, Chen W, et al.
Int J Mol Sci . 2023 Jun; 24(12). PMID: 37372979
TRIM28/KAP1/TIF1β is a crucial epigenetic modifier. Genetic ablation of is embryonic lethal, although RNAi-mediated knockdown in somatic cells yields viable cells. Reduction in TRIM28 abundance at the cellular or organismal...
16.
Li M, Coumar M, Lin S, Lin Y, Huang G, Chen C, et al.
J Med Chem . 2023 Feb; 66(4):2566-2588. PMID: 36749735
The development of orally bioavailable, furanopyrimidine-based double-mutant (L858R/T790M) EGFR inhibitors is described. First, selectivity for mutant EGFR was accomplished by replacing the ()-2-phenylglycinol moiety of with either an ethanol or...
17.
Lin S, Huang W, Chou S, Chen H, Wu Y
J Phys Chem Lett . 2022 Nov; 13(44):10439-10446. PMID: 36326470
The observation that the to ratio (OPR) of interstellar HO is smaller than 3 is an important yet unresolved subject in astronomy. We irradiated O embedded in solid H at...
18.
Lin S, Tien Y, Ke Y, Chang Y, Chang H, Ou L, et al.
Bioorg Chem . 2022 Jun; 128:105905. PMID: 35710525
We identified, via high-throughput screening using a FLIPR® calcium assay, compound 1, which incorporated a dihydroquinolinyl-2-oxoethylsulfanyl-(1H,5H)-pyrimidinedione core and activated the μ-opioid receptor (MOR) in the presence of naloxone or naltrexone....
19.
Yang T, Li T, Huang R, Pan M, Lin S, Lin S, et al.
J Cell Biol . 2022 Apr; 221(6). PMID: 35446349
Subcellular localization of the deubiquitinating enzyme BAP1 is deterministic for its tumor suppressor activity. While the monoubiquitination of BAP1 by an atypical E2/E3-conjugated enzyme UBE2O and BAP1 auto-deubiquitination are known...
20.
Lin S, Chou S, Tseng C, Wu Y
Spectrochim Acta A Mol Biomol Spectrosc . 2022 Apr; 276:121233. PMID: 35405375
Electron bombardment of aniline (PhNH) in an Ar matrix mainly generated the aniline cation (PhNH), anilino (PhNH) and phenyl (Ph) radicals, and phenylnitrene (PhN). Further irradiation of the electron-bombarded matrix...