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Shu-Huei Hsiao

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Articles 23
Citations 353
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Recent Articles
1.
Chen Y, Wang Y, Chen C, Huang C, Hsu C, Hsiao S, et al.
J Physiol Investig . 2024 Sep; 67(6):344-354. PMID: 39324984
Myeloproliferative neoplasms (MPNs) are blood cancers caused by mutations that originate from hematopoietic stem cells. More than 50%-90% of MPN patients had a dominant negative valine (V) to phenylalanine (F)...
2.
Sun C, Chen G, He B, Fu W, Lee C, Leu Y, et al.
Biochem Biophys Res Commun . 2022 Jan; 594:109-116. PMID: 35081499
HIC1 and RassF1A methylation, which cause loss of gene function, are found in various cancers, including renal cell carcinoma (RCC), and could alter cell stiffness and the content of extracellular...
3.
Chen C, He B, Chen Y, Lee K, Tung C, Hsu C, et al.
Int J Mol Sci . 2018 Sep; 19(10). PMID: 30249017
Cell stiffness is a potential biomarker for monitoring cellular transformation, metastasis, and drug resistance development. Environmental factors relayed into the cell may result in formation of inheritable markers (e.g., DNA...
4.
Chen C, Chiu C, Lee K, Hsu C, Chen H, Huang T, et al.
Biochem Biophys Res Commun . 2017 Oct; 494(3-4):470-476. PMID: 29066347
Negative valine (V) to phenylalanine (F) switch at the Janus kinase (JAK2) 617 codon (V617F) is the dominant driver mutation in patients with myeloproliferative neoplasms (MPNs). JAK2V617F was proved to...
5.
Chen H, Huang H, Chen Y, Lee K, Chu Y, Lin P, et al.
Ann Surg Oncol . 2015 Dec; 24(2):578-585. PMID: 26671036
Background: Methylation changes within tumor suppressor (TS) genes or polycomb group target (PcG) genes alter cell fates. Chromatin associated with PcG targets is bivalent in stem cells, while TS genes...
6.
Chen C, Lee K, Pai M, Chu P, Hsu C, Chiu C, et al.
Cancer Cell Int . 2015 Oct; 15:98. PMID: 26464562
Background And Propose: Changes in DNA methylation are associated with changes in somatic cell fate without the alteration of coding sequences. In addition to its use as a traceable biomarker,...
7.
Leu Y, Chu P, Chen C, Yeh K, Liu Y, Lee Y, et al.
Biochem Biophys Res Commun . 2014 Sep; 453(3):338-44. PMID: 25264105
Fetal alcohol syndrome (FAS) is a birth defect due to maternal alcohol consumption during pregnancy. Because mesenchymal stem cells (MSCs) are the main somatic stem cells in adults and may...
8.
Chen Y, Kuo M, Lin P, Chuang W, Hsu C, Chu P, et al.
Biochem Biophys Res Commun . 2013 Nov; 442(1-2):56-61. PMID: 24211627
Endosulfine alpha (ENSA) is an endogenous ligand of sulfonylurea receptor that was reported to be associated with an ATP-dependent potassium channel that controls insulin release and the onset of type...
9.
Lee C, Wong T, Yu-Wai Chan J, Lu S, Lin P, Cheng A, et al.
J Pathol . 2013 Jan; 230(3):298-309. PMID: 23362108
The strong associations between oral squamous cell carcinoma (OSCC) and dietary habits such as alcohol consumption (A), betel quid chewing (B) and cigarette smoking (C) and its predominance in men...
10.
Leu Y, Huang T, Hsiao S
Adv Exp Med Biol . 2012 Sep; 754:195-211. PMID: 22956503
Mesenchymal stem cells (MSCs) are multipotent stem cells of mesodermal origin that can be isolated from various sources and induced into different cell types. Although MSCs possess immune privilege and...