Show-Li Chen
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Explore the profile of Show-Li Chen including associated specialties, affiliations and a list of published articles.
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Articles
66
Citations
818
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Recent Articles
1.
Hsieh Y, Chen S
Bio Protoc
. 2024 Oct;
14(19):e5076.
PMID: 39399590
The neuromuscular junction (NMJ) is an interface between motor neurons and skeletal muscle fibers, facilitating the transmission of signals that initiate muscle contraction. Its pivotal role lies in ensuring efficient...
2.
Chen H, Lin C, Han Y, Huang Y, Liu Y, Hsu W, et al.
J Cachexia Sarcopenia Muscle
. 2024 Sep;
15(6):2559-2573.
PMID: 39323088
Background: Nuclear receptor interaction protein (NRIP) is versatile and engages with various proteins to execute its diverse biological function. NRIP deficiency was reported to cause small myofibre size in adult...
3.
Chen H, Yeo H, Huang Y, Tsai L, Lai H, Tsao Y, et al.
Skelet Muscle
. 2024 Jul;
14(1):17.
PMID: 39044305
Background: Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron (MN) degeneration, leading to neuromuscular junction (NMJ) dismantling and severe muscle atrophy. The nuclear receptor interaction protein (NRIP) functions...
4.
Lu Y, Ho T, Huang C, Yeh S, Chen S, Tsao Y
Bone Joint Res
. 2024 Mar;
13(4):137-148.
PMID: 38555936
Aims: Pigment epithelium-derived factor (PEDF) is known to induce several types of tissue regeneration by activating tissue-specific stem cells. Here, we investigated the therapeutic potential of PEDF 29-mer peptide in...
5.
Sun M, Ho T, Yeh S, Chen S, Tsao Y
Exp Eye Res
. 2023 Dec;
238:109743.
PMID: 38056550
Pigment epithelium-derived factor (PEDF) is widely recognized as a neuroprotective factor expressed in the retina and has shown therapeutic potential in several retinal diseases. Our study aimed to identify the...
6.
Yeh S, Ho T, Chu T, Chen S, Tsao Y
Cornea
. 2023 Nov;
43(3):378-386.
PMID: 38015979
Purpose: The purpose of this study was to extensively evaluate the efficacy of integrin αvβ3 antagonists for the treatment of experimental dry eye (EDE). Methods: Vitronectin, an αvβ3 ligand, was...
7.
Ho T, Fan N, Yeh S, Chen S, Tsao Y
Transl Vis Sci Technol
. 2022 Oct;
11(10):12.
PMID: 36201200
Purpose: To evaluate the efficacy of a pigment epithelium-derived factor (PEDF)-derived short peptide 29-mer, on the treatment and prevention of experimental dry eye (EDE). Methods: C57BL/6 mice were housed in...
8.
Chen H, Lu H, Chang C, Lin S, Huang C, Wei P, et al.
Stem Cell Res Ther
. 2022 Apr;
13(1):160.
PMID: 35410459
Background: Breast carcinoma-amplified sequence 2 (BCAS2) regulates β-catenin gene splicing. The conditional knockout of BCAS2 expression in the forebrain (BCAS2 cKO) of mice confers impaired learning and memory along with...
9.
Ho T, Yeh S, Chen S, Chu T, Tsao Y
BMC Ophthalmol
. 2022 Feb;
22(1):88.
PMID: 35193548
Background: Pigment epithelial-derived factor (PEDF), a 50 kDa secreted glycoprotein, exhibits distinct effects on a range of cell types. PEDF has been shown to inhibit vascular endothelial growth factor (VEGF)-mediated...
10.
Ho T, Yeh S, Chen S, Tsao Y
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445121
Cell signaling mediated by the αv integrin plays a pivotal role in macrophage activation in various inflammatory processes, but its involvement in the pathogenesis of dry eye disease (DED) remains...