Shoumo Bhattacharya
Overview
Explore the profile of Shoumo Bhattacharya including associated specialties, affiliations and a list of published articles.
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95
Citations
4014
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Recent Articles
1.
Kelm N, Kespohl M, Smagurauskaite G, Vales S, Karuppanan K, Mburu P, et al.
Basic Res Cardiol
. 2025 Feb;
PMID: 40009121
Myocarditis, an inflammatory disease of the heart muscle, is often triggered by viral infections. This inflammation, which can lead to severe cardiac dysfunction and adverse outcomes, is mediated by various...
2.
Davies B, Trelfa L, Rashbrook V, Drydale E, Martin R, Bai B, et al.
Transgenic Res
. 2024 Aug;
33(5):415-426.
PMID: 39088185
Mouse models with complex genetic backgrounds are increasingly used in preclinical research to accurately model human disease and to enable temporal and cell-specific evaluation of genetic manipulations. Backcrossing mice onto...
3.
Vales S, Kryukova J, Chandra S, Smagurauskaite G, Payne M, Clark C, et al.
Nat Commun
. 2023 Sep;
14(1):5763.
PMID: 37717048
CC and CXC-chemokines are the primary drivers of chemotaxis in inflammation, but chemokine network redundancy thwarts pharmacological intervention. Tick evasins promiscuously bind CC and CXC-chemokines, overcoming redundancy. Here we show...
4.
Bhattacharya S, Nuttall P
Front Cell Infect Microbiol
. 2021 Nov;
11:769542.
PMID: 34746035
Chemokines are structurally related proteins that activate leucocyte migration in response to injury or infection. Tick saliva contains chemokine-binding proteins or evasins which likely neutralize host chemokine function and inflammation....
5.
Singh K, Davies G, Alenazi Y, Eaton J, Kawamura A, Bhattacharya S
Sci Rep
. 2021 Jul;
11(1):14361.
PMID: 34234172
No abstract available.
6.
Singh K, Fang H, Davies G, Wright B, Lockstone H, Williams R, et al.
Front Immunol
. 2021 Mar;
12:640837.
PMID: 33746983
Inflammatory cardiomyopathy covers a group of diseases characterized by inflammation and dysfunction of the heart muscle. The immunosuppressive agents such as prednisolone, azathioprine and cyclosporine are modestly effective treatments, but...
7.
Moreira L, Takawale A, Hulsurkar M, Menassa D, Antanaviciute A, Lahiri S, et al.
Nature
. 2020 Nov;
587(7834):460-465.
PMID: 33149301
Atrial fibrillation, the most common cardiac arrhythmia, is an important contributor to mortality and morbidity, and particularly to the risk of stroke in humans. Atrial-tissue fibrosis is a central pathophysiological...
8.
Johnson A, Schneider J, Mohun T, Williams T, Bhattacharya S, Henderson D, et al.
J Cardiovasc Dev Dis
. 2020 Jul;
7(3).
PMID: 32717817
Congenital cardiovascular malformation is a common birth defect incorporating abnormalities of the outflow tract and aortic arch arteries, and mice deficient in the transcription factor () present with complex defects...
9.
Darlot B, Eaton J, Geis-Asteggiante L, Yakala G, Karuppanan K, Davies G, et al.
J Biol Chem
. 2020 May;
295(32):10926-10939.
PMID: 32471866
Chemokines mediate leukocyte migration and homeostasis and are key targets in inflammatory diseases including atherosclerosis, cytokine storm, and chronic autoimmune disease. Chemokine redundancy and ensuing network robustness has frustrated therapeutic...
10.
Bhattacharya S, Kawamura A
Adv Protein Chem Struct Biol
. 2020 Jan;
119:1-38.
PMID: 31997766
Inflammation, is driven by a network comprising cytokines, chemokines, their target receptors and leukocytes, and is a major pathologic mechanism that adversely affects organ function in diverse human diseases. Despite...