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Sho Tokumaru

Explore the profile of Sho Tokumaru including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 823
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Recent Articles
11.
Dai X, Sayama K, Shirakata Y, Tokumaru S, Yang L, Tohyama M, et al.
J Dermatol Sci . 2007 Dec; 50(1):53-60. PMID: 18077140
Background: 1 alpha,25-Dihydroxyvitamin D3 (1 alpha,25(OH)2D3), the active form of vitamin D, suppresses keratinocyte proliferation, promotes keratinocyte differentiation, and induces involucrin expression. Peroxisome proliferation-activated receptors (PPARs) are ligand-activated transcription factors....
12.
Tohyama M, Sayama K, Komatsuzawa H, Hanakawa Y, Shirakata Y, Dai X, et al.
Int Immunol . 2007 Sep; 19(9):1095-102. PMID: 17855433
The epidermis is constantly exposed to a variety of microbial pathogens and plays a vital role in resisting them. Soluble CXC chemokine ligand (CXCL) 16, which is one of the...
13.
Nagai H, Tokumaru S, Sayama K, Shirakata Y, Hanakawa Y, Hirakawa S, et al.
J Dermatol . 2007 Aug; 34(8):523-30. PMID: 17683382
Platelet-derived growth factor (PDGF) is involved in wound healing, but PDGF-induced fibroblast migration and the intracellular signaling mechanisms of fibroblast migration are poorly understood. Signal transducer and activator of transcription...
14.
Dai X, Sayama K, Shirakata Y, Hanakawa Y, Yamasaki K, Tokumaru S, et al.
J Invest Dermatol . 2007 Mar; 127(7):1728-35. PMID: 17330131
Signal transducers and activators of transcription (STATs) are critical to growth factor-mediated intracellular signal transduction. We observed the rapid expression and activation of STAT5a during keratinocyte differentiation induced by suspension...
15.
Shirakata Y, Kishimoto J, Tokumaru S, Yamasaki K, Hanakawa Y, Tohyama M, et al.
J Dermatol Sci . 2006 Sep; 45(1):69-72. PMID: 16996251
No abstract available.
16.
Yang L, Shirakata Y, Shudou M, Dai X, Tokumaru S, Hirakawa S, et al.
Cell Tissue Res . 2006 Jun; 326(1):69-77. PMID: 16758181
The presence of pre-existing basement membrane (BM) components improves the morphogenesis of epidermis and BM in constructing a human living skin-equivalent (LSE). De-epithelialized amniotic membrane (AM) retains key BM components....
17.
Sayama K, Hanakawa Y, Nagai H, Shirakata Y, Dai X, Hirakawa S, et al.
J Biol Chem . 2006 Jun; 281(31):22013-22020. PMID: 16754690
Transforming growth factor-beta-activated kinase 1 (TAK1) is a member of the mitogen-activated protein (MAP) kinase family and is an upstream signaling molecule of nuclear factor-kappaB (NF-kappaB). Given that NF-kappaB regulates...
18.
Dai X, Sayama K, Yamasaki K, Tohyama M, Shirakata Y, Hanakawa Y, et al.
J Invest Dermatol . 2006 Apr; 126(7):1574-81. PMID: 16628196
Toll-like receptor (TLR)3 is a receptor for virus-associated double-stranded RNA, and triggers antiviral immune responses during viral infection. Epidermal keratinocytes express TLR3 and provide an innate immune defense against viral...
19.
Yahata Y, Shirakata Y, Tokumaru S, Yang L, Dai X, Tohyama M, et al.
J Biol Chem . 2006 Mar; 281(19):13209-13216. PMID: 16543233
The role of angiotensin II (Ang II) in the control of systemic blood pressure and volume homeostasis is well known and has been extensively studied. Recently, Ang II was suggested...
20.
Yang L, Yamasaki K, Shirakata Y, Dai X, Tokumaru S, Yahata Y, et al.
J Dermatol Sci . 2006 Jan; 42(2):111-9. PMID: 16442268
Background: Bone morphogenetic protein-2 (BMP-2) and Wnt are involved in the normal development and tumorigenesis of several organs, and in the development of skin and skin appendages as a morphogen....