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Shiyu Xu

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Articles 59
Citations 375
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Recent Articles
1.
Zhang H, Sun S, Liu J, Guo Q, Meng L, Chen J, et al.
Cell . 2025 Mar; 188(5):1378-1392.e18. PMID: 40054448
The amphipod Hirondellea gigas is a dominant species inhabiting the deepest part of the ocean (∼6,800-11,000 m), but little is known about its genetic adaptation and population dynamics. Here, we...
2.
Xiao X, Zhao W, Song Z, Qi Q, Wang B, Zhu J, et al.
Cell . 2025 Mar; 188(5):1363-1377.e9. PMID: 40054447
Systematic exploration of the hadal zone, Earth's deepest oceanic realm, has historically faced technical limitations. Here, we collected 1,648 sediment samples at 6-11 km in the Mariana Trench, Yap Trench,...
3.
Zhang Y, Yang Z, Dai K, Hu B, Xu S, Wang Y, et al.
Toxins (Basel) . 2024 Sep; 16(9). PMID: 39330865
cytolethal distending toxin (CDT) can induce cell cycle arrest and apoptosis. Our laboratory's previous work demonstrated that GTPase 4b (Rab4b) is a key host protein implicated in CDT-induced cytotoxicity. This...
4.
Yao J, Guo Z, Qi D, Xu S, Lin W, Cheng L, et al.
Adv Sci (Weinh) . 2024 Aug; 11(41):e2403854. PMID: 39120051
Compressed ultrafast photography (CUP) can capture irreversible or difficult-to-repeat dynamic scenes at the imaging speed of more than one billion frames per second, which is obtained by compressive sensing-based image...
5.
Mo C, Li H, Yan M, Xu S, Wu J, Li J, et al.
Cell Metab . 2024 Aug; 36(8):1839-1857.e12. PMID: 39111287
Lungs can undergo facultative regeneration, but handicapped regeneration often leads to fibrosis. How microenvironmental cues coordinate lung regeneration via modulating cell death remains unknown. Here, we reveal that the neurotransmitter...
6.
Li G, Xu S, Messerlian C, Zhang Y, Chen Y, Sun Y, et al.
J Hazard Mater . 2024 Aug; 477:135411. PMID: 39111173
Disinfection byproducts (DBPs) have demonstrated cardiovascular and reproductive toxicity. However, the associations and mechanisms of DBP exposure in relation to hypertension among healthy young men, which are critical for gaining...
7.
Hart J, Pan H, Siddique S, Schnitzer N, Mallayya K, Xu S, et al.
Proc Natl Acad Sci U S A . 2024 Aug; 121(33):e2402129121. PMID: 39106309
We study the coupled charge density wave (CDW) and insulator-to-metal transitions in the 2D quantum material 1T-TaS. By applying in situ cryogenic 4D scanning transmission electron microscopy with in situ...
8.
Huang Y, Xu S, Wan T, Wang X, Jiang S, Shi W, et al.
Nutrients . 2024 Jul; 16(14). PMID: 39064691
Background: We aimed to comprehensively assess the relationship of specific dietary patterns and various nutrients with chronic kidney disease (CKD) and its progression. Methods: The observational study data were from...
9.
Xu S, Shen L, Zhang M, Jiang C, Zhang X, Xu Y, et al.
Bioinformatics . 2024 Jun; 40(7). PMID: 38905501
Motivation: In the field of drug discovery, accurately and effectively predicting the binding affinity between proteins and ligands is crucial for drug screening and optimization. However, current research primarily utilizes...
10.
Xu S, Chen Y, Gong Y
Foods . 2024 Jun; 13(11). PMID: 38890991
In diabetes mellitus, disordered glucose and lipid metabolisms precipitate diverse complications, including nonalcoholic fatty liver disease, contributing to a rising global mortality rate. Theaflavins (TFs) can improve disorders of glycolipid...