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Shivendra V Singh

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Articles 184
Citations 9723
Followers 0
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Recent Articles
1.
Yuan J, Kensler T, Dacic S, Hartman D, Wang R, Balogh P, et al.
Cancer Prev Res (Phila) . 2025 Mar; PMID: 40041932
Experimental studies have shown dietary isothiocyanates reduced cellular proliferative marker Ki-67 and increased apoptotic markers Caspase-3 and TUNEL in animals, but human data are lacking. The present study was to...
2.
Kim S, Singh S
Pharm Res . 2024 Oct; 41(10):1921-1932. PMID: 39375243
Purpose: We have shown previously that benzyl isothiocyanate (BITC) derived from cruciferous vegetables inhibits self-renewal of breast cancer stem-like cells (bCSC). The current study provides insights into the mechanism of...
3.
Kusza D, Venter G, Mabunda M, Biwi J, Samanta S, Klinck J, et al.
ChemMedChem . 2024 Mar; 19(12):e202400087. PMID: 38532643
Ajoene is an organosulfur compound found in crushed garlic that exerts its anti-cancer activity by S-thiolating cysteine residues on proteins. Its development is hampered due to limited bioavailability, so in...
4.
Mathan S, Singh R, Kim S, Singh S, Singh R
Cancers (Basel) . 2024 Jan; 16(2). PMID: 38254868
Despite advances in therapeutic approaches, the five-year survival rate for head and neck squamous cell carcinoma (HNSCC) patients is still less than fifty percent. Research has indicated that the consumption...
5.
Hahm E, Kim S, Pore S, Mathan S, Singh R, Singh S
Mol Carcinog . 2023 Nov; 63(2):301-313. PMID: 37921547
Bone is the most favored site for metastasis for each major subtype of breast cancer. Therapeutic modalities for alleviation of clinical symptoms associated with bone metastasis include surgical resection, radiation,...
6.
Kim S, Hahm E, Singh S
Mol Carcinog . 2023 Jun; 62(10):1449-1459. PMID: 37265428
Forkhead Box Q1 (FoxQ1) transcription factor is overexpressed in luminal-type and basal-type human breast cancers when compared to normal mammary tissue. This transcription factor is best known for its role...
7.
Hahm E, Kim S, Singh S
Mol Carcinog . 2023 Apr; 62(7):1051-1061. PMID: 37067392
Bone is the most prone to metastatic spread of breast cancer cells for each subtype of the disease. Bone metastasis-related complications including severe pain and pathological fractures affect patients' quality...
8.
Singh K, Hahm E, Kim S, Singh S
Cancer Prev Res (Phila) . 2022 Oct; 16(1):5-16. PMID: 36251722
Prevention Relevance: The present study shows that breast cancer prevention by WA in rats is associated with suppression of fatty acid synthesis.
9.
Hahm E, Mathan S, Singh R, Singh S
J Cancer Prev . 2022 Jul; 27(2):101-111. PMID: 35864856
Diallyl trisulfide (DATS) is an attractive anti-cancer phytochemical with in vitro and in vivo growth inhibitory effects against different solid tumors including breast cancer. We have shown previously that an...
10.
Kim S, Singh S
Mol Carcinog . 2022 May; 61(8):752-763. PMID: 35512572
Diallyl trisulfide (DATS) is a promising small molecule phytochemical that exhibits in vitro and in vivo activity in multiple preclinical solid tumor models including breast cancer, but the underlying mechanism...