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Shivam K Purohit

Explore the profile of Shivam K Purohit including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 15
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Recent Articles
1.
Purohit S, Stern L, Corbett A, Mak J, Fairlie D, Slobedman B, et al.
PLoS Pathog . 2024 Aug; 20(8):e1012372. PMID: 39110717
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that respond to riboflavin biosynthesis and cytokines through TCR-dependent and -independent pathways, respectively. MAIT cell activation plays an immunoprotective role against...
2.
Spiteri A, Wishart C, Pinget G, Purohit S, Macia L, King N, et al.
Immunol Cell Biol . 2024 Feb; 102(4):280-291. PMID: 38421112
Natural killer (NK) cells are cytotoxic lymphocytes important for viral defense. West Nile virus (WNV) infection of the central nervous system (CNS) causes marked recruitment of bone marrow (BM)-derived monocytes,...
3.
Purohit S, Corbett A, Slobedman B, Abendroth A
Front Immunol . 2023 Apr; 14:1121714. PMID: 37006246
Introduction: Mucosal Associated Invariant T (MAIT) cells are innate-like T cells that respond to conserved pathogen-derived vitamin B metabolites presented by the MHC class I related-1 molecule (MR1) antigen presentation...
4.
Samer C, Traves R, Purohit S, Abendroth A, McWilliam H, Slobedman B
Crit Rev Immunol . 2022 Apr; 41(5):49-67. PMID: 35381139
Mucosal-associated invariant T (MAIT) cells are abundant innate-like T cells important in antimicrobial immunity. These cells express a semi-invariant T cell receptor that recognizes the Major Histocompatibility Complex (MHC) class...
5.
Purohit S, Samer C, McWilliam H, Traves R, Steain M, McSharry B, et al.
J Infect Dis . 2021 Oct; 227(3):391-401. PMID: 34648018
The antigen presentation molecule MR1 (major histocompatibility complex, class I-related) presents ligands derived from the riboflavin (vitamin B) synthesis pathway, which is not present in mammalian species or viruses, to...