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Shitong He

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Citations 46
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Recent Articles
1.
Wang Y, Zhu X, Zhang H, He S, Liu Y, Zhao W, et al.
Molecules . 2024 Aug; 29(15). PMID: 39124958
Constructing heterostructures from already synthesized two-dimensional materials is of significant importance. We performed a first-principles study to investigate the electronic properties and interfacial characteristics of Janus MoSH/WSiN van der Waals...
2.
Fu Y, Zhan X, You X, Nie D, Mai H, Chen Y, et al.
PLoS Pathog . 2023 Dec; 19(12):e1011827. PMID: 38039266
[This corrects the article DOI: 10.1371/journal.ppat.1011480.].
3.
Wang P, Zhao J, Tan Y, Sheng J, He S, Chen Y, et al.
Theranostics . 2023 Jul; 13(11):3509-3523. PMID: 37441600
CD4 T cells play an important role in body development and homeostasis. Quantitative and functional changes in CD4 T cells result in abnormal immune responses, which lead to inflammation, cancer,...
4.
Fu Y, Zhan X, You X, Nie D, Mai H, Chen Y, et al.
PLoS Pathog . 2023 Jul; 19(7):e1011480. PMID: 37410794
Deubiquitinating enzymes (DUBs) regulate antiviral immune response through targeting DNA sensor signaling pathway members. As one of the DNA sensors, interferon (IFN)-γ inducible protein 16 (IFI16) play a major role...
5.
Du X, Sheng J, Chen Y, He S, Yang Y, Huang Y, et al.
Sci Signal . 2023 Jun; 16(788):eabm1756. PMID: 37279284
Innate immune signaling in macrophages during viral infection is regulated by ISGylation, the covalent attachment of the ubiquitin-like protein interferon-stimulated gene 15 (ISG15) to protein targets. Here, we explored the...
6.
Zhu X, Wang P, Zhan X, Zhang Y, Sheng J, He S, et al.
Cell Mol Immunol . 2023 Jan; 20(3):252-263. PMID: 36600049
The balance between inflammatory T helper type 17 (Th17) and immunosuppressive regulatory T (Treg) cells is critical for maintaining immune homeostasis in the human body and is tightly regulated under...
7.
Zhan X, He Q, Sheng J, Jiang X, Lin L, Huang Y, et al.
Immunology . 2022 Jul; 167(4):544-557. PMID: 35898171
The relative abundance of myeloid-derived suppressor cells (MDSCs) compared to cytotoxic T cells determines the outcomes of diseases and the efficacy of immunotherapy. Ubiquitin-specific peptidase 12 (USP12), a member of...
8.
Zhan X, Jiang X, He Q, Zhong L, Wang Y, Huang Y, et al.
Cent Eur J Immunol . 2022 May; 47(1):30-40. PMID: 35600157
Chronic inflammation develops when the immune system is unable to clear a persistent insult. Unresolved chronic inflammation leads to immunosuppression to maintain the internal homeostatic conditions, which is mediated primarily...
9.
Huang Y, He S, Chen Y, Sheng J, Fu Y, Du X, et al.
J Inflamm Res . 2022 Feb; 15:735-746. PMID: 35153498
Background: As deubiquitinases (DUBs), ubiquitin C-terminal hydrolase (UCH)-L1 has been shown to play a crucial role in regulating diverse biological processes. However, its function in macrophage polarization remains unclear. Methods:...
10.
Fu Y, Wang P, Zhao J, Tan Y, Sheng J, He S, et al.
Cell Death Differ . 2021 May; 28(10):2857-2870. PMID: 33941870
Deubiquitinases (DUBs) regulate diverse biological processes and represent a novel class of drug targets. However, the biological function of only a small fraction of DUBs, especially in adaptive immune response...