Shirley Hui
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Explore the profile of Shirley Hui including associated specialties, affiliations and a list of published articles.
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15
Citations
1377
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Recent Articles
1.
Pai S, Hui S, Weber P, Narayan S, Whitley O, Li P, et al.
Cereb Cortex
. 2023 Apr;
33(13):8581-8593.
PMID: 37106565
An open challenge in human genetics is to better understand the systems-level impact of genotype variation on developmental cognition. To characterize the genetic underpinnings of peri-adolescent cognition, we performed genotype-phenotype...
2.
Deniffel D, McAlpine K, Harder F, Jain R, Lawson K, Healy G, et al.
Eur Radiol
. 2023 Apr;
33(8):5840-5850.
PMID: 37074425
Objectives: Previous trial results suggest that only a small number of patients with non-metastatic renal cell carcinoma (RCC) benefit from adjuvant therapy. We assessed whether the addition of CT-based radiomics...
3.
Pai S, Weber P, Isserlin R, Kaka H, Hui S, Shah M, et al.
F1000Res
. 2021 Feb;
9:1239.
PMID: 33628435
Patient classification based on clinical and genomic data will further the goal of precision medicine. Interpretability is of particular relevance for models based on genomic data, where sample sizes are...
4.
Lawson K, Sousa C, Zhang X, Kim E, Akthar R, Caumanns J, et al.
Nature
. 2020 Sep;
586(7827):120-126.
PMID: 32968282
The genetic circuits that allow cancer cells to evade destruction by the host immune system remain poorly understood. Here, to identify a phenotypically robust core set of genes and pathways...
5.
Sun R, Hui S, Bader G, Lin X, Kraft P
PLoS Genet
. 2019 Mar;
15(3):e1007530.
PMID: 30875371
A common complementary strategy in Genome-Wide Association Studies (GWAS) is to perform Gene Set Analysis (GSA), which tests for the association between one phenotype of interest and an entire set...
6.
Pai S, Hui S, Isserlin R, Shah M, Kaka H, Bader G
Mol Syst Biol
. 2019 Mar;
15(3):e8497.
PMID: 30872331
Patient classification has widespread biomedical and clinical applications, including diagnosis, prognosis, and treatment response prediction. A clinically useful prediction algorithm should be accurate, generalizable, be able to integrate diverse data...
7.
Sharma S, Huang R, Hui S, Smith M, Chung P, Schwartzman A, et al.
J Robot Surg
. 2017 Nov;
12(3):481-485.
PMID: 29181777
In recent years, fluorescent cholangiography using Indocyanine green (ICG) dye has been used to aid identification of structures during robotic cholecystectomy. We sought to compare cholecystectomy with ICG dye versus...
8.
Michailidou K, Lindstrom S, Dennis J, Beesley J, Hui S, Kar S, et al.
Nature
. 2017 Oct;
551(7678):92-94.
PMID: 29059683
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer...
9.
Milne R, Kuchenbaecker K, Michailidou K, Beesley J, Kar S, Lindstrom S, et al.
Nat Genet
. 2017 Oct;
49(12):1767-1778.
PMID: 29058716
Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease. We conducted a GWAS using 21,468 ER-negative cases and 100,594...
10.
Tariq H, Gaduputi V, Peralta R, Abbas N, Nayudu S, Thet P, et al.
Can J Gastroenterol Hepatol
. 2016 Jul;
2016:8198047.
PMID: 27446870
Aim. To study serum triglyceride level as a predictor of complications and outcomes in acute pancreatitis. Methods. In this retrospective observational study, 582 patients admitted with acute pancreatitis, who had...