Shira Kahlon
Overview
Explore the profile of Shira Kahlon including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
225
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0
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Recent Articles
1.
Kotzur R, Kahlon S, Isaacson B, Gamliel M, Charpak-Amikam Y, Lieberman J, et al.
PLoS Pathog
. 2024 Jan;
20(1):e1011923.
PMID: 38215172
Natural killer cells (NKs) found during pregnancy at the maternal-fetal interface named decidual (d)NKs, show signs of education following first pregnancy, resulting in better placentation and fetus-growth, hence termed pregnancy...
2.
Kotzur R, Stein N, Kahlon S, Berhani O, Isaacson B, Mandelboim O
iScience
. 2023 Aug;
26(8):107284.
PMID: 37609636
Natural killer (NK) cells are currently used in clinical trials to treat tumors. However, such therapies still suffer from problems such as donor variability, reproducibility, and more, which prevent a...
3.
Kol I, Rishiq A, Cohen M, Kahlon S, Pick O, Dassa L, et al.
J Cell Biol
. 2023 Jun;
222(9).
PMID: 37389656
The GPI-anchoring pathway plays important roles in normal development and immune modulation. MHC Class I Polypeptide-related Sequence A (MICA) is a stress-induced ligand, downregulated by human cytomegalovirus (HCMV) to escape...
4.
Seidel E, Dassa L, Kahlon S, Tirosh B, Halenius A, Seidel Malkinson T, et al.
Nat Commun
. 2021 Apr;
12(1):2061.
PMID: 33824318
Stress can induce cell surface expression of MHC-like ligands, including MICA, that activate NK cells. Human cytomegalovirus (HCMV) glycoprotein US9 downregulates the activating immune ligand MICA*008 to avoid NK cell...
5.
Elias S, Kol I, Kahlon S, Amore R, Zeibak M, Mevorach D, et al.
Haematologica
. 2020 May;
106(7):1846-1856.
PMID: 32467141
Anti-RhD antibodies are widely used in clinical practice to prevent immunization against RhD, principally in hemolytic disease of the fetus and newborn. Intriguingly, this disease is induced by production of...
6.
Elias S, Kahlon S, Duev-Cohen A, Mandelboim O
J Vis Exp
. 2019 Jan;
(143).
PMID: 30663643
Interactions between receptors and ligands constitute a fundamental biological process. However, direct experiments with cells that express the native receptor and the ligand are challenging since the ligand of a...
7.
Berhani O, Glasner A, Kahlon S, Duev-Cohen A, Yamin R, Horwitz E, et al.
Eur J Immunol
. 2018 Dec;
49(2):228-241.
PMID: 30536875
Natural killer (NK) cells are innate lymphocytes that efficiently eliminate cancerous and infected cells. NKp46 is an important NK activating receptor shown to participate in recognition and activation of NK...
8.
Elias S, Kahlon S, Kotzur R, Kaynan N, Mandelboim O
Oncoimmunology
. 2018 Jun;
7(6):e1428158.
PMID: 29872553
Treatment with monoclonal antibodies has revolutionized clinical medicine, especially in the fields of cancer and immunology. One of the oldest antibodies, which is widely used for the treatment of lymphomas...
9.
Kahlon S, Shreibman D, Unger T, Ben-Yehuda D, Elias S
Blood Cancer J
. 2018 May;
8(5):48.
PMID: 29795444
No abstract available.
10.
Trager U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, et al.
Brain
. 2014 Jan;
137(Pt 3):819-33.
PMID: 24459107
Huntington's disease is an inherited neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin gene. The peripheral innate immune system contributes to Huntington's disease pathogenesis and has been...