Shinichi Kohsaka
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Explore the profile of Shinichi Kohsaka including associated specialties, affiliations and a list of published articles.
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112
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5821
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Recent Articles
1.
Ren X, He J, Li S, Hu H, Kyle M, Kohsaka S, et al.
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201584
Monocytes are circulating macrophage precursors generated from bone marrow hematopoietic stem cells. In adults, monocytes continuously replenish cerebral border-associated macrophages under physiological conditions. Monocytes also rapidly infiltrate the brain in...
2.
Ren X, He J, Hu H, Kohsaka S, Zhao L
bioRxiv
. 2024 May;
PMID: 38798506
Monocytes are circulating macrophage precursors and are generated from bone marrow hematopoietic stem cells. In the adults, monocytes continuously replenish cerebral border-associated macrophages under a physiological condition. Monocytes also rapidly...
3.
Kurematsu C, Sawada M, Ohmuraya M, Tanaka M, Kuboyama K, Ogino T, et al.
J Exp Med
. 2022 Mar;
219(4).
PMID: 35297954
New neurons, continuously added in the adult olfactory bulb (OB) and hippocampus, are involved in information processing in neural circuits. Here, we show that synaptic pruning of adult-born neurons by...
4.
Mishima T, Nagai T, Yahagi K, Akther S, Oe Y, Monai H, et al.
eNeuro
. 2019 Aug;
6(5).
PMID: 31444225
Transcranial direct current stimulation (tDCS) has been reported for its beneficial effects on memory formation and various brain disorders. While the electrophysiological readout of tDCS effects is subtle, astrocytes have...
5.
Sanagi T, Sasaki T, Nakagaki K, Minamimoto T, Kohsaka S, Ichinohe N
Front Cell Neurosci
. 2019 Aug;
13:344.
PMID: 31417364
Autism spectrum disorder (ASD) is one of the most widespread neurodevelopmental disorders, characterized by impairment in social interactions, and restricted stereotyped behaviors. Using immunohistochemistry and positron emission tomography (PET), several...
6.
Madry C, Kyrargyri V, Arancibia-Carcamo I, Jolivet R, Kohsaka S, Bryan R, et al.
Neuron
. 2018 Jan;
97(2):299-312.e6.
PMID: 29290552
Microglia exhibit two modes of motility: they constantly extend and retract their processes to survey the brain, but they also send out targeted processes to envelop sites of tissue damage....
7.
Kikuchi R, Hamanoue M, Koshimoto M, Kohsaka S, Nakajima K
Neurochem Res
. 2017 Nov;
43(2):324-339.
PMID: 29164431
The responses of inhibitory neurons/synapses to motoneuron injury in the cranial nervous system remain to be elucidated. In this study, we analyzed GABA receptor (GABAR) and GABAergic neurons at the...
8.
Doolen S, Cook J, Riedl M, Kitto K, Kohsaka S, Honda C, et al.
Glia
. 2017 Aug;
65(12):1976-1989.
PMID: 28850719
The complement 3a receptor (C3aR1) participates in microglial signaling under pathological conditions and was recently shown to be activated by the neuropeptide TLQP-21. We previously demonstrated that TLQP-21 elicits hyperalgesia...
9.
Fuger P, Hefendehl J, Veeraraghavalu K, Wendeln A, Schlosser C, Obermuller U, et al.
Nat Neurosci
. 2017 Aug;
20(10):1371-1376.
PMID: 28846081
To clarify the role of microglia in brain homeostasis and disease, an understanding of their maintenance, proliferation and turnover is essential. The lifespan of brain microglia, however, remains uncertain, and...
10.
Tomioka I, Ishibashi H, Minakawa E, Motohashi H, Takayama O, Saito Y, et al.
eNeuro
. 2017 Apr;
4(2).
PMID: 28374014
Age-associated neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and the polyglutamine (polyQ) diseases, are becoming prevalent as a consequence of elongation of the human lifespan. Although various rodent models...