Shinichi Kiyonari
Overview
Explore the profile of Shinichi Kiyonari including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
417
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0
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Recent Articles
1.
Yamashita K, Kiyonari S, Tsubota S, Kishida S, Sakai R, Kadomatsu K
Cancer Sci
. 2020 May;
111(7):2431-2439.
PMID: 32415892
MYCN gene amplification is consistently associated with poor prognosis in patients with neuroblastoma, a pediatric tumor arising from the sympathetic nervous system. Conventional anticancer drugs, such as alkylating agents and...
2.
Mayanagi K, Ishino S, Shirai T, Oyama T, Kiyonari S, Kohda D, et al.
Sci Rep
. 2018 Nov;
8(1):16209.
PMID: 30385773
In Eukarya and Archaea, the lagging strand synthesis is accomplished mainly by three key factors, DNA polymerase (Pol), flap endonuclease (FEN), and DNA ligase (Lig), in the DNA replication process....
3.
Su Z, Kishida S, Tsubota S, Sakamoto K, Cao D, Kiyonari S, et al.
Oncotarget
. 2018 Jan;
8(63):106296-106310.
PMID: 29290949
Neurocan (NCAN), a secreted chondroitin sulfate proteoglycan, is one of the major inhibitory molecules for axon regeneration in nervous injury. However, its role in cancer is not clear. Here we...
4.
Tsubota S, Kishida S, Shimamura T, Ohira M, Yamashita S, Cao D, et al.
Cancer Res
. 2017 Aug;
77(19):5259-5271.
PMID: 28807939
Pediatric cancers such as neuroblastoma are thought to involve a dysregulation of embryonic development. However, it has been difficult to identify the critical events that trigger tumorigenesis and differentiate them...
5.
Kitao H, Kiyonari S, Iimori M, Niimi S, Kataoka Y, Akiyama S, et al.
Gan To Kagaku Ryoho
. 2016 Jun;
43(6):707-14.
PMID: 27306806
Platinum-based chemotherapeutic drugs as a component of combination chemotherapy are widely used in the treatment of cancer. In particular, oxaliplatin(L-OHP), one such platinum-based chemotherapeutic drug, has a synergistic effect in...
6.
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al.
Nat Commun
. 2016 Apr;
7:11117.
PMID: 27030108
Temporal regulation of microtubule dynamics is essential for proper progression of mitosis and control of microtubule plus-end tracking proteins by phosphorylation is an essential component of this regulation. Here we...
7.
Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa-Ichinose T, Miura D, et al.
Mol Cancer Ther
. 2015 Jul;
14(10):2332-42.
PMID: 26208523
Platinum-based chemotherapeutic drugs are widely used as components of combination chemotherapy in the treatment of cancer. One such drug, oxaliplatin, exerts a synergistic effect against advanced colorectal cancer in combination...
8.
Matsuoka K, Iimori M, Niimi S, Tsukihara H, Watanabe S, Kiyonari S, et al.
Mol Cancer Ther
. 2015 Feb;
14(4):1004-13.
PMID: 25700705
Trifluridine (FTD) is a key component of the novel oral antitumor drug TAS-102, which consists of FTD and a thymidine phosphorylase inhibitor. Like 5-fluoro-2'-deoxyuridine (FdUrd), a deoxynucleoside form of 5-fluorouracil...
9.
Shiraishi M, Ishino S, Yamagami T, Egashira Y, Kiyonari S, Ishino Y
Nucleic Acids Res
. 2015 Feb;
43(5):2853-63.
PMID: 25694513
DNA is constantly damaged by endogenous and environmental influences. Deaminated adenine (hypoxanthine) tends to pair with cytosine and leads to the A:T→G:C transition mutation during DNA replication. Endonuclease V (EndoV)...
10.
Nakaguro M, Kiyonari S, Kishida S, Cao D, Murakami-Tonami Y, Ichikawa H, et al.
Cancer Sci
. 2015 Jan;
106(3):237-43.
PMID: 25557119
Neuroblastoma (NB) is a childhood malignant tumor that arises from precursor cells of the sympathetic nervous system. Spontaneous regression is a phenomenon unique to NBs and is caused by differentiation...