Shin-Yu Chen
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Explore the profile of Shin-Yu Chen including associated specialties, affiliations and a list of published articles.
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25
Citations
177
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Recent Articles
1.
Baek H, Das D, Chen S, Li H, Arur S
Cell Rep
. 2025 Jan;
44(1):115157.
PMID: 39792558
ERK activity oscillates between sustained activation during oocyte formation and transient inactivation during oocyte maturation, fertilization, and early embryogenesis. Consequences of ectopic ERK activity upon oocyte maturation and in early...
2.
Huang Y, Hsu C, Hou C, Chen S, Tain Y
Nutrients
. 2024 Dec;
16(23).
PMID: 39683469
Background: Resveratrol is recognized as a promising nutraceutical with antihypertensive and prebiotic properties; however, its bioavailability in vivo is limited. To enhance its bioactivity, we developed resveratrol butyrate esters (RBEs)....
3.
Ortega J, Wahba L, Seemann J, Chen S, Fire A, Arur S
Sci Adv
. 2024 Oct;
10(40):eadp0466.
PMID: 39356768
Pachytene piRNAs, a Piwi-interacting RNA subclass in mammals, are hypothesized to regulate non-transposon sequences during spermatogenesis. piRNAs, the 21URNAs, are implicated in regulating coding sequences; the messenger RNA targets and...
4.
Chien R, Chen S, Mishchuk D, Slupsky C
Int J Med Mushrooms
. 2023 Oct;
25(11):27-40.
PMID: 37831510
Mushrooms have two components, the fruiting body, which encompasses the stalk and the cap, and the mycelium, which supports the fruiting body underground. The part of the mushroom most commonly...
5.
Chen S, Tseng J, Wu C, Lin S
Foods
. 2023 Aug;
12(15).
PMID: 37569194
In the process of making mushrooms into vacuum-fried crisps, the resulting blanched broth (BB) and centrifuged broth (CB) are often discarded, thereby increasing the amount of wastewater and treatment costs....
6.
Reyes-Castro R, Chen S, Seemann J, Kundu S, Gibbons D, Arur S
Sci Adv
. 2023 Jul;
9(30):eadf6210.
PMID: 37494452
KRAS/ERK pathway phosphorylates DICER1, causing its nuclear translocation, and phosphomimetic contributes to tumorigenesis in mice. Mechanisms through which phospho-DICER1 regulates tumor progression remain undefined. While DICER1 canonically regulates microRNAs (miRNA)...
7.
Trimmer K, Zhao P, Seemann J, Chen S, Mondal S, Ben-Yakar A, et al.
Cell Rep
. 2023 May;
42(6):112544.
PMID: 37227820
Maternal RNAs are stored from minutes to decades in oocytes throughout meiosis I arrest in a transcriptionally quiescent state. Recent reports, however, propose a role for nascent transcription in arrested...
8.
Yang G, Jena P, Hu Y, Sheng L, Chen S, Slupsky C, et al.
Biomark Res
. 2023 Feb;
11(1):20.
PMID: 36803569
Background: Aging and diet are risks for metabolic diseases. Bile acid receptor farnesoid X receptor (FXR) knockout (KO) mice develop metabolic liver diseases that progress into cancer as they age,...
9.
Haversat J, Woglar A, Klatt K, Akerib C, Roberts V, Chen S, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(21):e2117865119.
PMID: 35576467
Crossover formation is essential for proper segregation of homologous chromosomes during meiosis. Here, we show that Caenorhabditis elegans cyclin-dependent kinase 2 (CDK-2) partners with cyclin-like protein COSA-1 to promote crossover...
10.
Sotelo-Orozco J, Chen S, Hertz-Picciotto I, Slupsky C
Front Mol Biosci
. 2021 Jul;
8:682134.
PMID: 34307452
Blood is a rich biological sample routinely collected in clinical and epidemiological studies. With advancements in high throughput -omics technology, such as metabolomics, epidemiology can now delve more deeply and...