Shin-Ichi Tominaga
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Explore the profile of Shin-Ichi Tominaga including associated specialties, affiliations and a list of published articles.
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48
Citations
1715
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Recent Articles
1.
Tsuda H, Tominaga S, Ohtsuki M, Komine M
J Dermatol Sci
. 2022 Feb;
105(2):113-120.
PMID: 35105507
Background: IL-33 is a dual-functional molecule; it acts as a cytokine to enhance type 2 inflammation, and as a nuclear factor. The roles of nuclear IL-33 are not yet fully...
2.
Kikuchi M, Takase K, Hayakawa M, Hayakawa H, Tominaga S, Ohmori T
Mol Brain
. 2020 May;
13(1):74.
PMID: 32393354
Psychoneuroimmunological studies have clearly demonstrated that both cellular and humoral immunity are related to major depression. Soluble ST2 is regarded as a key molecule regulating immune system as well as...
3.
Ohto-Ozaki H, Hayakawa M, Kamoshita N, Maruyama T, Tominaga S, Ohmori T
J Immunol
. 2020 Mar;
204(8):2033-2042.
PMID: 32144162
IκBζ (encoded by the ) is a member of the nuclear IκB family, which is involved in the expression of secondary response genes based on signals from TLR or IL-1R....
4.
Sakai K, Nagashima S, Wakabayashi T, Tumenbayar B, Hayakawa H, Hayakawa M, et al.
Arterioscler Thromb Vasc Biol
. 2018 Oct;
38(11):2590-2600.
PMID: 30354246
Objective- Inhibition of HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase) is atheroprotective primarily by decreasing plasma LDL (low-density lipoprotein)-cholesterol. However, it is unknown whether inhibition of HMGCR in myeloid cells contributes to this...
5.
Kamoshita N, Tominaga S
RNA
. 2018 Oct;
25(1):90-104.
PMID: 30337458
The translation of capsid proteins of Plautia stali intestine virus (PSIV), encoded in its second open reading frame (ORF2), is directed by an internal ribosomal entry site (IRES) located in...
6.
ST2 gene products critically contribute to cellular transformation caused by an oncogenic Ras mutant
Tago K, Ohta S, Kashiwada M, Funakoshi-Tago M, Matsugi J, Tominaga S, et al.
Heliyon
. 2017 Dec;
3(10):e00436.
PMID: 29226265
The ST2 gene was originally identified as a primary responsive gene, and the expressions of its gene products are induced by stimulation with growth factors and by oncogenic stresses. In...
7.
Hayakawa H, Hayakawa M, Tominaga S
Biochem Biophys Rep
. 2017 Sep;
5:401-407.
PMID: 28955848
Type 2 innate lymphoid cells (ILC2) in lungs produce interleukin (IL)-5 and IL-13 in response to IL-33 and may contribute to the development of allergic diseases such as asthma. However,...
8.
Tominaga S, Ohta S, Tago K
Biochem Biophys Rep
. 2017 Sep;
5:8-15.
PMID: 28955802
The ST2 gene is induced in murine fibroblast cells at the start of cell proliferation. Although IL-33 has been identified as a ligand for one of the two major gene...
9.
Ohmori T, Nagao Y, Mizukami H, Sakata A, Muramatsu S, Ozawa K, et al.
Sci Rep
. 2017 Jun;
7(1):4159.
PMID: 28646206
Haemophilia B, a congenital haemorrhagic disease caused by mutations in coagulation factor IX gene (F9), is considered an appropriate target for genome editing technology. Here, we describe treatment strategies for...
10.
Tago K, Ohta S, Funakoshi-Tago M, Aoki-Ohmura C, Matsugi J, Tominaga S, et al.
FEBS Open Bio
. 2017 Feb;
7(2):293-302.
PMID: 28174694
The ST2 gene was originally identified as a primary responsive gene induced by stimulation with growth factors and by oncogenic stress. The ST2 gene harbors two distinct promoters - a...