Shin-ichi Akiyama
Overview
Explore the profile of Shin-ichi Akiyama including associated specialties, affiliations and a list of published articles.
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91
Citations
1235
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Recent Articles
11.
Toyoda Y, Tabata S, Kishi J, Kuramoto T, Mitsuhashi A, Saijo A, et al.
Arthritis Rheumatol
. 2014 Feb;
66(3):560-8.
PMID: 24574215
Objective: Thymidine phosphorylase (TP) in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) is induced by tumor necrosis factor α (TNFα) and other cytokines that have been reported to be major inflammation...
12.
Yamamoto M, Arimura H, Fukushige T, Minami K, Nishizawa Y, Tanimoto A, et al.
Mol Cell Biol
. 2014 Jan;
34(6):1077-84.
PMID: 24421385
Abcb10, member 10 of the ABC transporter family, is reportedly a part of a complex in the mitochondrial inner membrane with mitoferrin-1 (Slc25a37) and ferrochelatase (Fech) and is responsible for...
13.
Ikeda R, Nishizawa Y, Tajitsu Y, Minami K, Mataki H, Masuda S, et al.
Oncol Rep
. 2013 Nov;
31(1):197-201.
PMID: 24173679
Major vault protein (MVP) is the main constituent of the vault ribonucleoprotein particle and is identical to lung resistance-related protein (LRP). Although MVP is also expressed in several types of...
14.
Tajitsu Y, Ikeda R, Nishizawa Y, Mataki H, Che X, Sumizawa T, et al.
Int J Mol Med
. 2013 Jul;
32(3):703-8.
PMID: 23820674
Major vault protein (MVP) is identical to lung resistance-related protein (LRP), which is the major component of vaults. Vaults are considered to play a protective role against xenobiotics and other...
15.
Ikeda R, Tabata S, Tajitsu Y, Nishizawa Y, Minami K, Furukawa T, et al.
Oncol Rep
. 2013 Jun;
30(3):1444-8.
PMID: 23807085
The angiogenic factor, platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP), stimulates the chemotaxis of endothelial cells and confers resistance to apoptosis induced by hypoxia. 2-Deoxy-D-ribose, a degradation product of thymidine...
16.
Wang J, Ikeda R, Che X, Ooyama A, Yamamoto M, Furukawa T, et al.
Int J Oncol
. 2013 Jun;
43(3):746-54.
PMID: 23807031
Prostacyclin synthase (PGIS or PTGIS) is an enzyme that catalyses the conversion of prostaglandin H2 (PGH2) to prostaglandin I2 (PGI2). PGI2 promotes cancer growth by activating peroxisome proliferator-activated receptor δ...
17.
Abe S, Morita Y, Kaneko M, Hanibuchi M, Tsujimoto Y, Goto H, et al.
J Immunol
. 2013 May;
190(12):6239-49.
PMID: 23690472
Podoplanin (Aggrus), which is a type I transmembrane sialomucin-like glycoprotein, is highly expressed in malignant pleural mesothelioma (MPM). We previously reported the generation of a rat anti-human podoplanin Ab, NZ-1,...
18.
Hirayama A, Nakashima E, Sugimoto M, Akiyama S, Sato W, Maruyama S, et al.
Anal Bioanal Chem
. 2012 Oct;
404(10):3101-9.
PMID: 23052862
Capillary electrophoresis coupled with time-of-flight mass spectrometry was used to explore new serum biomarkers with high sensitivity and specificity for diabetic nephropathy (DN) diagnosis, through comprehensive analysis of serum metabolites...
19.
Sato S, Hanibuchi M, Kuramoto T, Yamamori N, Goto H, Ogawa H, et al.
Clin Exp Metastasis
. 2012 Sep;
30(3):333-44.
PMID: 23011677
The organ microenvironment significantly affects the processes of cancer metastasis. Elucidating the molecular mechanisms of interaction between tumor cells and the organ microenvironment is crucial for the development of effective...
20.
Kuramoto T, Goto H, Mitsuhashi A, Tabata S, Ogawa H, Uehara H, et al.
Mol Cancer Ther
. 2012 Sep;
11(12):2578-87.
PMID: 22989420
Notch signaling regulates cell-fate decisions during development and postnatal life. Little is known, however, about the role of Delta-like-4 (Dll4)-Notch signaling between cancer cells, or how this signaling affects cancer...