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Shimaa H A Soliman

Explore the profile of Shimaa H A Soliman including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 54
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Recent Articles
1.
Cisneros W, Soliman S, Walter M, Simons L, Cornish D, De Fabritiis S, et al.
PLoS Pathog . 2024 Sep; 20(9):e1012083. PMID: 39259751
The persistence of HIV-1 in long-lived latent reservoirs during suppressive antiretroviral therapy (ART) remains one of the principal barriers to a functional cure. Blocks to transcriptional elongation play a central...
2.
Kajimura Y, Tessari A, Orlacchio A, Thoms A, Cufaro M, Di Marco F, et al.
bioRxiv . 2024 Jun; PMID: 38826292
The biological functions of the scaffold protein Ran Binding Protein 9 (RanBP9) remain elusive in macrophages or any other cell type where this protein is expressed together with its CTLH...
3.
Cisneros W, Walter M, Soliman S, Simons L, Cornish D, Halle A, et al.
bioRxiv . 2024 Mar; PMID: 38464055
The persistence of HIV-1 in long-lived latent reservoirs during suppressive antiretroviral therapy (ART) remains one of the principal barriers to a functional cure. Blocks to transcriptional elongation play a central...
4.
Soliman S, Cisneros W, Iwanaszko M, Aoi Y, Ganesan S, Walter M, et al.
Sci Adv . 2023 Mar; 9(10):eadf2468. PMID: 36888719
The polymerase-associated factor 1 complex (PAF1C) is a key, post-initiation transcriptional regulator of both promoter-proximal pausing and productive elongation catalyzed by RNA Pol II and is also involved in transcriptional...
5.
Aoi Y, Shah A, Ganesan S, Soliman S, Cho B, Goo Y, et al.
Mol Cell . 2022 Aug; 82(18):3412-3423.e5. PMID: 35973425
It is unclear how various factors functioning in the transcriptional elongation by RNA polymerase II (RNA Pol II) cooperatively regulate pause/release and productive elongation in living cells. Using an acute...
6.
Tessari A, Soliman S, Orlacchio A, Capece M, Amann J, Visone R, et al.
J Cancer Metastasis Treat . 2021 Nov; 6. PMID: 34778565
Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related deaths in the Western world. Despite progress made with targeted therapies and immune checkpoint inhibitors, the vast majority of...
7.
Rickels R, Wang L, Iwanaszko M, Ozark P, Morgan M, Piunti A, et al.
Genes Dev . 2020 Oct; 34(21-22):1493-1502. PMID: 33033055
Catalytic-inactivating mutations within the enhancer H3K4 mono-methyltransferase Trr and its mammalian homologs, MLL3/4, cause only minor changes in gene expression compared with whole-gene deletions for these COMPASS members. To identify...
8.
Soliman S, Stark A, Gardner M, Harshman S, Breece C, Amari F, et al.
Sci Rep . 2020 Apr; 10(1):7138. PMID: 32346083
The lack of tools to reliably detect RanBP9 in vivo has significantly hampered progress in understanding the biological functions of this scaffold protein. We report here the generation of a...