Shihong Max Gao
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Explore the profile of Shihong Max Gao including associated specialties, affiliations and a list of published articles.
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8
Citations
70
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Recent Articles
1.
Deng D, Guan Y, Mutlu A, Wang B, Gao S, Zheng H, et al.
Mol Biol Cell
. 2025 Jan;
36(3):br8.
PMID: 39878653
The endolysosomal system plays a crucial role in maintaining cellular homeostasis and promoting organism fitness. The pH of its acidic compartments is a crucial parameter for proper function, and it...
2.
Udeshi N, Xu C, Jiang Z, Gao S, Yin Q, Luo W, et al.
J Immunol
. 2024 Aug;
213(7):1023-1032.
PMID: 39132986
Dendritic cells (DCs) are specialized sentinel and APCs coordinating innate and adaptive immunity. Through proteins on their cell surface, DCs sense changes in the environment, internalize pathogens, present processed Ags,...
3.
Gao S, Qi Y, Zhang Q, Guan Y, Lee Y, Ding L, et al.
Nat Aging
. 2024 May;
4(7):998-1013.
PMID: 38816550
Organismal aging involves functional declines in both somatic and reproductive tissues. Multiple strategies have been discovered to extend lifespan across species. However, how age-related molecular changes differ among various tissues...
4.
Lee Y, Savini M, Chen T, Yang J, Zhao Q, Ding L, et al.
Dev Cell
. 2023 Sep;
58(23):2718-2731.e7.
PMID: 37708895
Healthy mitochondria are critical for reproduction. During aging, both reproductive fitness and mitochondrial homeostasis decline. Mitochondrial metabolism and dynamics are key factors in supporting mitochondrial homeostasis. However, how they are...
5.
Lee Y, Savini M, Chen T, Yang J, Zhao Q, Ding L, et al.
bioRxiv
. 2023 Apr;
PMID: 37066227
Healthy mitochondria are critical for reproduction. During aging, both reproductive fitness and mitochondrial homeostasis decline. Mitochondrial metabolism and dynamics are key factors in supporting mitochondrial homeostasis. However, how they are...
6.
Gao S, Qi Y, Zhang Q, Mohammed A, Lee Y, Guan Y, et al.
bioRxiv
. 2023 Mar;
PMID: 36909655
Organism aging occurs at the multicellular level; however, how pro-longevity mechanisms slow down aging in different cell types remains unclear. We generated single-cell transcriptomic atlases across the lifespan of Caenorhabditis...
7.
Zhao Q, Gao S, Wang M
Trends Biochem Sci
. 2020 Jul;
45(11):978-991.
PMID: 32624271
Lysosomes transcend the role of degradation stations, acting as key nodes for interorganelle crosstalk and signal transduction. Lysosomes communicate with the nucleus through physical proximity and functional interaction. In response...
8.
Mutlu A, Gao S, Zhang H, Wang M
Nat Commun
. 2020 Mar;
11(1):1450.
PMID: 32193370
Olfactory and metabolic dysfunctions are intertwined phenomena associated with obesity and neurodegenerative diseases; yet how mechanistically olfaction regulates metabolic homeostasis remains unclear. Specificity of olfactory perception integrates diverse environmental odors...
9.
Li B, Wong C, Gao S, Zhang R, Sun R, Li Y, et al.
Elife
. 2018 Sep;
7.
PMID: 30176986
The correct establishment and maintenance of unidirectional Notch signaling are critical for the homeostasis of various stem cell lineages. However, the molecular mechanisms that prevent cell-autonomous ectopic Notch signaling activation...