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Shih-Yuan Liu

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Articles 92
Citations 1062
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Recent Articles
11.
Zhang Y, Wang Z, Lamine W, Xu S, Li B, Chrostowska A, et al.
J Org Chem . 2023 Feb; 88(4):2415-2424. PMID: 36752741
The reaction mechanism of the Pd/Senphos-catalyzed -hydroboration reaction of 1,3-enynes was investigated using various experimental techniques, including deuterium and double crossover labeling experiments, X-ray crystallographic characterization of model reaction intermediates,...
12.
Chang H, Liu S, Lee M, Lee S, Wong C
J Formos Med Assoc . 2022 May; 121(12):2639-2643. PMID: 35577643
Sugammadex is a direct reversal agent of aminosteroid muscle relaxants, particularly rocuronium, with promptly and completely reverse of deep neuromuscular block (NMB), which allows better surgical conditions. Sugammadex exhibits advantages...
13.
Giustra Z, Chen G, Vasiliu M, Karkamkar A, Autrey T, Dixon D, et al.
RSC Adv . 2022 May; 11(54):34132-34136. PMID: 35497319
The reaction order and Arrhenius activation parameters for spontaneous hydrogen release from cyclic amine boranes, , BN-cycloalkanes, were determined for 1,2-BN-cyclohexane (1) and 3-methyl-1,2-BN-cyclopentane (2) in tetraglyme. Computational analysis identified...
14.
Liu Y, Puig de la Bellacasa R, Li B, Cuenca A, Liu S
J Am Chem Soc . 2021 Aug; 143(35):14059-14064. PMID: 34431676
The first α-boryl diazo compound that is capable of engaging in classic synthetic organic diazo reaction chemistry is described. The diazomethyl-1,2-azaborine , which is a BN isostere of phenyldiazomethane, is...
15.
Wang Z, Wu J, Lamine W, Li B, Sotiropoulos J, Chrostowska A, et al.
Angew Chem Int Ed Engl . 2021 Jul; 60(39):21231-21236. PMID: 34245074
A new family of carbon-bound boron enolates, generated by a kinetically controlled halogen exchange between chlorocatecholborane and silylketene acetals, is described. These C-boron enolates are demonstrated to activate 1,3-enyne substrates...
16.
Liu S, Ho Y, Wong C
Front Pharmacol . 2021 Jun; 12:683782. PMID: 34122111
Laparoscopic bariatric surgery is increasingly performed in morbidly obese patients. However, post-surgical pain is common and is usually managed with classical opioids such as morphine and fentanyl. Further, morbidly obese...
17.
Chen M, Unikela K, Ramalakshmi R, Li B, Darrigan C, Chrostowska A, et al.
Angew Chem Int Ed Engl . 2020 Oct; 60(3):1556-1560. PMID: 33021073
The first example of a BN-doped cycloparaphenylene BN-[10]CPP was synthesized and characterized. Its reactivity and photophysical properties were evaluated in direct comparison to its carbonaceous analogues Mes-[10]CPP and [10]CPP. While...
18.
Zhang Y, Li B, Liu S
Angew Chem Int Ed Engl . 2020 Jun; 59(37):15928-15932. PMID: 32511855
The first trans-selective cyanoboration reaction of an alkyne, specifically a 1,3-enyne, is described. The reported palladium-catalyzed cyanoboration of 1,3-enynes is site-, regio-, and diastereoselective, and is uniquely enabled by the...
19.
Boknevitz K, Darrigan C, Chrostowska A, Liu S
Chem Commun (Camb) . 2020 Mar; 56(26):3749-3752. PMID: 32125334
A BN indole-containing aromatic scaffold has been synthesized and the cation-π binding ability characterized by nuclear magnetic resonance (NMR) monitored titrations. The resulting chemical shifts were analyzed using a non-linear...
20.
Giustra Z, Yang X, Chen M, Bettinger H, Liu S
Angew Chem Int Ed Engl . 2019 Oct; 58(52):18918-18922. PMID: 31604006
We provide a seminal example of the utility of the 1,2-azaborine motif as a 4C+1N+1B synthon in organic synthesis. Specifically, conditions for the practically scalable photoisomerization of 1,2-azaborine in a...