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Shih-Feng You

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Articles 6
Citations 119
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Recent Articles
1.
Iyer A, Vermunt L, Mirfakhar F, Minaya M, Acquarone M, Koppisetti R, et al.
medRxiv . 2024 May; PMID: 38798451
Neuronal dysfunction has been extensively studied as a central feature of neurodegenerative tauopathies. However, across neurodegenerative diseases, there is strong evidence for active involvement of immune cells like microglia in...
2.
Filipello F, You S, Mirfakhar F, Mahali S, Bollman B, Acquarone M, et al.
Acta Neuropathol . 2023 Apr; 145(6):749-772. PMID: 37115208
TREM2 is an innate immune receptor expressed by microglia in the adult brain. Genetic variation in the TREM2 gene has been implicated in risk for Alzheimer's disease and frontotemporal dementia,...
3.
Brase L, You S, DOliveira Albanus R, Del-Aguila J, Dai Y, Novotny B, et al.
Nat Commun . 2023 Apr; 14(1):2314. PMID: 37085492
Genetic studies of Alzheimer disease (AD) have prioritized variants in genes related to the amyloid cascade, lipid metabolism, and neuroimmune modulation. However, the cell-specific effect of variants in these genes...
4.
You S, Brase L, Filipello F, Iyer A, Del-Aguila J, He J, et al.
medRxiv . 2023 Feb; PMID: 36798226
Genome-wide association studies (GWAS) have identified many modifiers of Alzheimer disease (AD) risk enriched in microglia. Two of these modifiers are common variants in the locus (rs1582763: protective and rs6591561:...
5.
Chao P, Liu W, You S, Li P
Sci Rep . 2018 Sep; 8(1):14470. PMID: 30262836
Shear wave elastography (SWE) has been widely adopted for clinical in vivo imaging of tissue elasticity for disease diagnosis, and this modality can be a valuable tool for in vitro...
6.
Prigge C, Yeh P, Liou N, Lee C, You S, Liu L, et al.
J Neurosci . 2016 Jul; 36(27):7184-97. PMID: 27383593
Unlabelled: Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs, with five subtypes named M1-M5) are a unique subclass of RGCs with axons that project directly to many brain nuclei involved in...