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Shi-Jin Zhang

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Recent Articles
11.
Andersson D, Fauconnier J, Yamada T, Lacampagne A, Zhang S, Katz A, et al.
J Physiol . 2011 Apr; 589(Pt 7):1791-801. PMID: 21486840
The sympathetic adrenergic system plays a central role in stress signalling and stress is often associated with increased production of reactive oxygen species (ROS). Furthermore, the sympathetic adrenergic system is...
12.
Andersson D, Fauconnier J, Park C, Zhang S, Thireau J, Ivarsson N, et al.
Antioxid Redox Signal . 2011 Mar; 15(9):2455-64. PMID: 21381862
Aims: Heart disease is commonly associated with altered mitochondrial function and signs of oxidative stress. This study elucidates whether primary cardiac mitochondrial dysfunction causes changes in cardiomyocyte handling of reactive...
13.
Bruton J, Aydin J, Yamada T, Shabalina I, Ivarsson N, Zhang S, et al.
J Physiol . 2010 Sep; 588(Pt 21):4275-88. PMID: 20837639
Mammals exposed to a cold environment initially generate heat by repetitive muscle activity (shivering). Shivering is successively replaced by the recruitment of uncoupling protein-1 (UCP1)-dependent heat production in brown adipose...
14.
Yamada T, Zhang S, Westerblad H, Katz A
Am J Physiol Endocrinol Metab . 2010 Jun; 299(3):E364-73. PMID: 20516259
Blood ketone body levels increase during starvation and untreated diabetes. Here we tested the hypothesis that ketone bodies directly inhibit insulin action in skeletal muscle. We investigated the effect of...
15.
Zhang S, Sandstrom M, Ahlsen M, Ivarsson N, Zhu H, Ma J, et al.
Exp Physiol . 2010 May; 95(8):892-8. PMID: 20472648
2-Methoxyoestradiol (2-ME) is an oestrogen derivative that inhibits superoxide dismutase (which converts superoxide anions to H(2)O(2)). Since reactive oxygen species have been implicated in glucose transport, we determined the effect...
16.
Yamada T, Place N, Kosterina N, Ostberg T, Zhang S, Grundtman C, et al.
Arthritis Rheum . 2009 Oct; 60(11):3280-9. PMID: 19877058
Objective: Progressive muscle weakness is a common feature in patients with rheumatoid arthritis (RA). However, little is known about whether the intrinsic contractile properties of muscle fibers are affected in...
17.
Place N, Yamada T, Zhang S, Westerblad H, Bruton J
J Physiol . 2009 Aug; 587(Pt 19):4717-24. PMID: 19675072
Intense activation of skeletal muscle results in fatigue development, which involves impaired function of the muscle cells resulting in weaker and slower contractions. Intense muscle activity also results in increased...
18.
Salomonsson S, Grundtman C, Zhang S, Lanner J, Li C, Katz A, et al.
Muscle Nerve . 2009 Feb; 39(5):674-82. PMID: 19229963
Expression of major histocompatibility complex (MHC) class I in skeletal muscle fibers is an early and consistent finding in inflammatory myopathies. To test if MHC class I has a primary...
19.
Lanner J, Bruton J, Assefaw-Redda Y, Andronache Z, Zhang S, Severa D, et al.
FASEB J . 2009 Jan; 23(6):1728-38. PMID: 19141536
The involvement of Ca(2+) in the insulin-mediated signaling cascade, resulting in glucose uptake in skeletal muscle, is uncertain. Here, we test the hypothesis that Ca(2+) influx through canonical transient receptor...
20.
Aydin J, Shabalina I, Place N, Reiken S, Zhang S, Bellinger A, et al.
FASEB J . 2008 Aug; 22(11):3919-24. PMID: 18687806
When acutely exposed to a cold environment, mammals shiver to generate heat. During prolonged cold exposure, shivering is replaced by adaptive adrenergic nonshivering thermogenesis with increased heat production in brown...