Shelly Heimfeld
Overview
Explore the profile of Shelly Heimfeld including associated specialties, affiliations and a list of published articles.
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58
Citations
6267
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Recent Articles
11.
Turtle C, Hanafi L, Berger C, Gooley T, Cherian S, Hudecek M, et al.
J Clin Invest
. 2016 Apr;
126(6):2123-38.
PMID: 27111235
Background: T cells that have been modified to express a CD19-specific chimeric antigen receptor (CAR) have antitumor activity in B cell malignancies; however, identification of the factors that determine toxicity...
12.
Blau C, Ramirez A, Blau S, Pritchard C, Dorschner M, Schmechel S, et al.
J Natl Compr Canc Netw
. 2016 Jan;
14(1):8-17.
PMID: 26733551
Accelerating cancer research is expected to require new types of clinical trials. This report describes the Intensive Trial of OMics in Cancer (ITOMIC) and a participant with triple-negative breast cancer...
13.
Bleakley M, Heimfeld S, Loeb K, Jones L, Chaney C, Seropian S, et al.
J Clin Invest
. 2015 Jun;
125(7):2677-89.
PMID: 26053664
Background: Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (HCT). In mice, naive T cells (TN) cause more severe GVHD than...
14.
Qu X, Davison J, Du L, Storer B, Stirewalt D, Heimfeld S, et al.
Epigenetics
. 2015 May;
10(6):526-35.
PMID: 25996682
Aberrant DNA methylation is known to occur in cancer, including hematological malignancies such as acute myeloid leukemia (AML). However, less is known about whether specific methylation profiles characterize specific subcategories...
15.
McCune J, Mager D, Bemer M, Sandmaier B, Storer B, Heimfeld S
Cancer Chemother Pharmacol
. 2015 May;
76(1):85-96.
PMID: 25983023
Purpose: Fludarabine monophosphate (fludarabine) is an integral component of many reduced-intensity conditioning regimens for hematopoietic cell transplantation (HCT). Fludarabine's metabolite, 9-β-D-arabinofuranosyl-2-fluoroadenine (F-ara-A), undergoes cellular uptake and activation to form the...
16.
Pollack S, Jones R, Farrar E, Lai I, Lee S, Cao J, et al.
J Immunother Cancer
. 2014 Oct;
2(1):36.
PMID: 25317334
Background: Adoptive T cell therapy represents an attractive modality for the treatment of patients with cancer. Peripheral blood mononuclear cells have been used as a source of antigen specific T...
17.
Kim M, Tan Y, Cheng W, Kingsbury T, Heimfeld S, Civin C
Br J Haematol
. 2014 Oct;
168(4):583-97.
PMID: 25312678
Expression levels of MIR144 and MIR451 increase during erythropoiesis, a pattern that is conserved from zebrafish to humans. As these two miRs are expressed from the same polycistronic transcript, we...
18.
Zhou X, Gao F, Shu Z, Chung J, Heimfeld S, Gao D
Biopreserv Biobank
. 2014 May;
8(3):147-52.
PMID: 24836483
Determination of cell hydraulic conductivity (Lp) is required to predict the optimal conditions for cell cryopreservation. One of the critical procedures associated with the determination of Lp is to measure...
19.
Zhou X, Kang X, Shu Z, Chen H, Ding W, Du P, et al.
Biopreserv Biobank
. 2014 May;
7(2):107-14.
PMID: 24835682
The cooling process is critical for the cryopreservation of human hematopoietic stem cells (HSCs). Currently, programmed freezing methods and uncontrolled cooling methods are in use, both having obvious disadvantages. In...
20.
Bleakley M, Heimfeld S, Jones L, Turtle C, Krause D, Riddell S, et al.
Biol Blood Marrow Transplant
. 2014 Feb;
20(5):705-16.
PMID: 24525279
Graft-versus-host disease (GVHD) is a frequent major complication of allogeneic hematopoietic cell transplantation (HCT). Approaches that selectively deplete T cells that cause GVHD from allogeneic stem cell grafts and preserve...