Sheetal Bhatara
Overview
Explore the profile of Sheetal Bhatara including associated specialties, affiliations and a list of published articles.
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3
Citations
3
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0
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Recent Articles
1.
Yang J, Zheng Z, Jiao Y, Yu K, Bhatara S, Yang X, et al.
Nat Methods
. 2025 Mar;
PMID: 40074951
Spatial transcriptomics (ST) has advanced our understanding of tissue regionalization by enabling the visualization of gene expression within whole-tissue sections, but current approaches remain plagued by the challenge of achieving...
2.
Mavuluri J, Dhungana Y, Jones L, Bhatara S, Shi H, Yang X, et al.
Cancer Discov
. 2025 Feb;
PMID: 39998425
Chimeric antigen receptor (CAR)-T cell therapies, while promising for CD19+ hematological malignancies, often face setbacks due to relapses. Our research identifies GPR65 as a tumor-specific determinant affecting the efficacy of...
3.
Escherich C, Moriyama T, Li Z, Hsiao Y, Hsiao Y, Yang W, et al.
Blood
. 2025 Jan;
145(11):1182-1194.
PMID: 39791601
Inotuzumab ozogamicin (InO) is an antibody-calicheamicin conjugate with striking efficacy in B-cell acute lymphoblastic leukemia (B-ALL). However, there is wide interpatient variability in treatment response, and the genetic basis of...
4.
Kang T, Lan X, Mi T, Chen H, Alli S, Lim S, et al.
Science
. 2024 Oct;
386(6718):eadl4492.
PMID: 39388542
Epigenetic reinforcement of T cell exhaustion is known to be a major barrier limiting T cell responses during immunotherapy. However, the core epigenetic regulators restricting antitumor immunity during prolonged antigen...
5.
Huang X, Li Y, Zhang J, Yan L, Zhao H, Ding L, et al.
Cancer Cell
. 2024 Apr;
42(4):552-567.e6.
PMID: 38593781
Leukemia can arise at various stages of the hematopoietic differentiation hierarchy, but the impact of developmental arrest on drug sensitivity is unclear. Applying network-based analyses to single-cell transcriptomes of human...
6.
Yan K, Condori J, Ma Z, Metais J, Ju B, Ding L, et al.
Sci Adv
. 2023 Oct;
9(40):eadg9959.
PMID: 37801507
Lentiviral vector (LV)-based gene therapy holds promise for a broad range of diseases. Analyzing more than 280,000 vector integration sites (VISs) in 273 samples from 10 patients with X-linked severe...