Shaun D McCullough
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Explore the profile of Shaun D McCullough including associated specialties, affiliations and a list of published articles.
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26
Citations
244
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Recent Articles
11.
Faber S, McCullough S
Appl In Vitro Toxicol
. 2019 Aug;
4(2):115-128.
PMID: 31380467
With 7 million deaths reported annually from air pollution alone, it is evident that adverse effects of inhaled toxicant exposures remain a major public health concern in the 21st century....
12.
Zavala J, Ledbetter A, Morgan D, Dailey L, Puckett E, McCullough S, et al.
Inhal Toxicol
. 2018 Aug;
30(4-5):169-177.
PMID: 30086657
A cell culture exposure system (CCES) was developed to expose cells established at an air-liquid interface (ALI) to volatile chemicals. We characterized the CCES by exposing indigo dye-impregnated filter inserts...
13.
Bowers E, McCullough S, Morgan D, Dailey L, Diaz-Sanchez D
Sci Rep
. 2018 Jun;
8(1):9398.
PMID: 29925859
Inter-individual variability is observed in all biological responses; however this variability is difficult to model and its underlying mechanisms are often poorly understood. This issue currently impedes understanding the health...
14.
Angrish M, Allard P, McCullough S, Druwe I, Helbling Chadwick L, Hines E, et al.
Environ Health Perspect
. 2018 Apr;
126(4):045001.
PMID: 29669403
Background: The epigenome may be an important interface between environmental chemical exposures and human health. However, the links between epigenetic modifications and health outcomes are often correlative and do not...
15.
Hargrove M, J Snow S, Luebke R, Wood C, Krug J, Krantz Q, et al.
Environ Sci Technol
. 2018 Feb;
52(5):3062-3070.
PMID: 29384667
Air pollution is a diverse and dynamic mixture of gaseous and particulate matter, limiting our understanding of associated adverse health outcomes. The biological effects of two simulated smog atmospheres (SA)...
16.
Cote I, McCullough S, Hines R, Vandenberg J
Curr Opin Toxicol
. 2018 Jan;
6:71-78.
PMID: 29333520
Despite the many recent advances in the field of epigenetics, application of this knowledge in environmental health risk assessment has been limited. In this paper, we identify opportunities for application...
17.
McCullough S, On D, Bowers E
Curr Protoc Toxicol
. 2017 May;
72:3.14.1-3.14.28.
PMID: 28463415
Histone modifications work in concert with DNA methylation to regulate cellular structure, function, and response to environmental stimuli. More than 130 unique histone modifications have been described to date, and...
18.
Walsh D, McCullough S, Yourstone S, Jones S, Cairns B, Jones C, et al.
PLoS One
. 2017 Mar;
12(3):e0173848.
PMID: 28358811
Background: Injury to the airways after smoke inhalation is a major mortality risk factor in victims of burn injuries, resulting in a 15-45% increase in patient deaths. Damage to the...
19.
Bowers E, McCullough S
Toxicol Sci
. 2017 Jan;
155(2):302-314.
PMID: 28049737
The epigenome is a dynamic mediator of gene expression that shapes the way that cells, tissues, and organisms respond to their environment. Initial studies in the emerging field of "toxicoepigenetics"...
20.
Harrill A, McCullough S, Wood C, Kahle J, Chorley B
Toxicol Sci
. 2016 Jul;
152(2):264-72.
PMID: 27462126
Biomarker measurements that reliably correlate with tissue injury and that can be measured within accessible biofluids offer benefits in terms of cost, time, and convenience when assessing chemical and drug-induced...