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Sharona Shleizer-Burko

Explore the profile of Sharona Shleizer-Burko including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 564
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Recent Articles
1.
Israeli A, Burko Y, Shleizer-Burko S, Zelnik I, Sela N, Hajirezaei M, et al.
PLoS Genet . 2021 Apr; 17(4):e1009537. PMID: 33901177
Morphogenesis and differentiation are important stages in organ development and shape determination. However, how they are balanced and tuned during development is not fully understood. In the compound leaved tomato,...
2.
Bakhtiari M, Park J, Ding Y, Shleizer-Burko S, Neuhausen S, Halldorsson B, et al.
Nat Commun . 2021 Apr; 12(1):2075. PMID: 33824302
Variable number tandem repeats (VNTRs) account for significant genetic variation in many organisms. In humans, VNTRs have been implicated in both Mendelian and complex disorders, but are largely ignored by...
3.
Mitra I, Huang B, Mousavi N, Ma N, Lamkin M, Yanicky R, et al.
Nature . 2021 Jan; 589(7841):246-250. PMID: 33442040
Autism spectrum disorder (ASD) is an early-onset developmental disorder characterized by deficits in communication and social interaction and restrictive or repetitive behaviours. Family studies demonstrate that ASD has a substantial...
4.
Feupe Fotsing S, Margoliash J, Wang C, Saini S, Yanicky R, Shleizer-Burko S, et al.
Nat Genet . 2019 Nov; 51(11):1652-1659. PMID: 31676866
Short tandem repeats (STRs) have been implicated in a variety of complex traits in humans. However, genome-wide studies of the effects of STRs on gene expression thus far have had...
5.
Mousavi N, Shleizer-Burko S, Yanicky R, Gymrek M
Nucleic Acids Res . 2019 Jun; 47(15):e90. PMID: 31194863
Tandem repeat (TR) expansions have been implicated in dozens of genetic diseases, including Huntington's Disease, Fragile X Syndrome, and hereditary ataxias. Furthermore, TRs have recently been implicated in a range...
6.
Bakhtiari M, Shleizer-Burko S, Gymrek M, Bansal V, Bafna V
Genome Res . 2018 Oct; 28(11):1709-1719. PMID: 30352806
Whole-genome sequencing is increasingly used to identify Mendelian variants in clinical pipelines. These pipelines focus on single-nucleotide variants (SNVs) and also structural variants, while ignoring more complex repeat sequence variants....
7.
Burko Y, Shleizer-Burko S, Yanai O, Shwartz I, Zelnik I, Jacob-Hirsch J, et al.
Plant Cell . 2013 Jun; 25(6):2070-83. PMID: 23771895
Flexible maturation rates underlie part of the diversity of leaf shape, and tomato (Solanum lycopersicum) leaves are compound due to prolonged organogenic activity of the leaf margin. The CINCINNATA-teosinte branched1,...
8.
Burko Y, Geva Y, Refael-Cohen A, Shleizer-Burko S, Shani E, Berger Y, et al.
Plant Cell Physiol . 2011 Jan; 52(3):518-27. PMID: 21257605
Plant architecture is a predictable but flexible trait. The timing and position of organ initiation from the shoot apical meristem (SAM) contribute to the final plant form. While much progress...
9.
Shleizer-Burko S, Burko Y, Ben-Herzel O, Ori N
Development . 2011 Jan; 138(4):695-704. PMID: 21228002
During their development, leaves progress through a highly controlled yet flexible developmental program. Transcription factors from the CIN-TCP family affect leaf shape by regulating the timing of leaf maturation. Characterization...
10.
Shani E, Ben-Gera H, Shleizer-Burko S, Burko Y, Weiss D, Ori N
Plant Cell . 2010 Oct; 22(10):3206-17. PMID: 20959562
Leaf shape diversity relies on transient morphogenetic activity in leaf margins. However, how this morphogenetic capacity is maintained is still poorly understood. Here, we uncover a role for the hormone...