Sharon A Riddler
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Explore the profile of Sharon A Riddler including associated specialties, affiliations and a list of published articles.
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76
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2616
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Recent Articles
1.
Riddler S, Benson C, Brinson C, Deeks S, DeJesus E, Mills A, et al.
Infect Dis Ther
. 2024 Sep;
13(11):2285-2299.
PMID: 39278975
Introduction: Vesatolimod is a Toll-like receptor-7 (TLR7) agonist in clinical development as part of a combination regimen for human immunodeficiency virus (HIV) cure. Influenza-like symptoms associated with TLR7-mediated immune activation...
2.
Morris B, Hixson E, Klamar-Blain C, Gillespie D, Abebe K, Rinaldo C, et al.
J Leukoc Biol
. 2024 Aug;
117(1).
PMID: 39217408
Twelve weeks of dipyridamole increased extracellular adenosine levels and decreased T cell activation in people with human immunodeficiency virus (HIV). In this analysis, we investigated the effect of dipyridamole on...
3.
West 3rd R, Oberly P, Saylor A, Riddler S, Nolin T, Devanathan A
J Chromatogr B Analyt Technol Biomed Life Sci
. 2024 Jun;
1241:124164.
PMID: 38823149
Although antiretroviral therapy (ART) is highly effective for the treatment of HIV-1 infection to suppress virus in the blood, HIV persists in tissues. HIV persistence in the tissues is due...
4.
Riddler S, Kelly C, Hoesley C, Ho K, Piper J, Edick S, et al.
J Infect Dis
. 2024 Apr;
230(3):696-705.
PMID: 38655842
Background: On-demand topical products could be an important tool for human immunodeficiency virus (HIV) prevention. We evaluated the safety, pharmacokinetics, and ex vivo pharmacodynamics of a tenofovir alafenamide/elvitegravir (TAF/EVG, 20 ...
5.
Crowell T, Ritz J, Zheng L, Naqvi A, Cyktor J, Puleo J, et al.
AIDS
. 2024 Mar;
38(8):1141-1152.
PMID: 38489580
Objective: To assess how antiretroviral therapy (ART) initiation during acute or early HIV infection (AEHI) affects the viral reservoir and host immune responses. Design: Single-arm trial of ART initiation during...
6.
West 3rd R, Oberly P, Riddler S, Nolin T, Devanathan A
J Pharm Biomed Anal
. 2024 Jan;
240:115932.
PMID: 38198884
Antiretroviral therapy (ART) is highly effective for the treatment of HIV-1 infection. ART previously consisted of concomitant administration of many drugs, multiple times per day. Currently, ART generally consists of...
7.
Cardone K, Dudek S, Keat K, Bradford Y, Cindi Z, Daar E, et al.
Pac Symp Biocomput
. 2023 Dec;
29:594-610.
PMID: 38160309
Access to safe and effective antiretroviral therapy (ART) is a cornerstone in the global response to the HIV pandemic. Among people living with HIV, there is considerable interindividual variability in...
8.
West 3rd R, Oberly P, Riddler S, Nolin T, Devanathan A
J Chromatogr B Analyt Technol Biomed Life Sci
. 2023 Oct;
1230:123905.
PMID: 37866010
Although current antiretroviral therapy (ART) effectively suppresses HIV in the blood, regimens may fail due to suboptimal treatment history and non-adherence to ART. In these scenarios, accumulation of viral resistance...
9.
Gandhi R, Bosch R, Mar H, Laird G, Halvas E, Hovind L, et al.
J Infect Dis
. 2023 Feb;
227(12):1376-1380.
PMID: 36763044
Fourteen people with human immunodeficiency virus type 1 had longitudinal measurements of intact, defective, and total proviral DNA over the course of two decades of antiretroviral therapy. Three patterns of...
10.
Maaske J, Sproule S, Falsey A, Sobieszczyk M, Luetkemeyer A, Paulsen G, et al.
Front Immunol
. 2023 Jan;
13:1062067.
PMID: 36713413
Background: Breakthrough severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in coronavirus disease 2019 (COVID-19) vaccinees typically produces milder disease than infection in unvaccinated individuals. Methods: To explore disease attenuation,...