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Sharmila Shanmuganad

Explore the profile of Sharmila Shanmuganad including associated specialties, affiliations and a list of published articles. Areas
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Citations 76
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Recent Articles
1.
Shanmuganad S, Ferguson A, Paranjpe A, Cianciolo E, Katz J, Herold M, et al.
bioRxiv . 2023 Mar; PMID: 36909576
Following their proliferative expansion and differentiation into effector cells like Th1, Tfh, and T central memory precursors (Tcmp), most effector CD4+ T cells die, while some survive and become memory...
2.
Shanmuganad S, Hummel S, Varghese V, Hildeman D
J Immunol . 2022 Jan; 208(3):651-659. PMID: 34996838
The precursors of TCRαβCD8αα intraepithelial lymphocytes (IEL) arise in the thymus through a complex process of agonist selection. We and others have shown that the proapoptotic protein, Bim, is critical...
3.
Li K, Ladle B, Kurtulus S, Sholl A, Shanmuganad S, Hildeman D
Cell Death Differ . 2019 Sep; 27(4):1214-1224. PMID: 31558776
Most effector CD8 T cells die, while some persist and become either "effector" (T) or "central" (T) memory T cells. Paradoxically, effector CD8 T cells with greater memory potential have...
4.
Li K, Shanmuganad S, Carroll K, Katz J, Jordan M, Hildeman D
Immunol Rev . 2017 May; 277(1):21-43. PMID: 28462527
T cells play a critical role in immune responses as they specifically recognize peptide/MHC complexes with their T-cell receptors and initiate adaptive immune responses. While T cells are critical for...
5.
Liao C, Zimmer M, Shanmuganad S, Yu H, Cardell S, Wang C
Gastroenterology . 2011 Nov; 142(2):326-34.e1-2. PMID: 22057113
Background & Aims: CD1d-restricted natural killer (NK) T cells are a subset of immunoregulatory T cells that comprise type I (express the semi-invariant T-cell receptor [TCR] and can be detected...
6.
Renthal N, Guidry P, Shanmuganad S, Renthal W, Stroynowski I
Immunogenetics . 2010 Oct; 63(1):57-64. PMID: 20967542
Although the human nonclassical class Ib major histocompatibility complex (Mhc) locus, HLA-G, is known to act as an immune suppressor in immune-privileged sites, little is currently known regarding participation of...