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Shaoting Chen

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Articles 12
Citations 76
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Recent Articles
1.
Zhai X, He X, Huang A, Liu Z, Chen S, Chang B, et al.
J Gastroenterol Hepatol . 2025 Jan; PMID: 39797719
Background: The mechanism underlying chronic drug-induced liver injury (DILI) remains unclear. Immune activation is a common feature of DILI progression and is closely associated with metabolism. We explored the immunometabolic...
2.
Chen S, Shen X, Cao P, Chen Q, Zhong R, Cao Y
Front Oncol . 2024 Nov; 14:1474701. PMID: 39497721
Introduction: This study aims to investigate the role of the m6A regulatory factor METTL3 in LUAD. Methods: By examining the expression of METTL3 in LUAD and conducting cellular functional experiments,...
3.
Hu L, Zhao X, He X, Guo Y, Cheng H, Chen S, et al.
Chin Med . 2024 May; 19(1):70. PMID: 38750545
Background: Gynostemma pentaphyllum (Thunb.) Makino, commonly known as "southern ginseng", contains high amounts of ginsenoside derivatives and exhibits similar biological activities with Panax ginseng (C. A. MEY) (ginseng), which is...
4.
Lu T, Chen F, Yao J, Bu Z, Kyani A, Liang B, et al.
J Med Chem . 2024 May; 67(10):8099-8121. PMID: 38722799
Nicotinamide phosphoribosyltransferase (NAMPT) is an attractive therapeutic target for treating select cancers. There are two forms of NAMPT: intracellular NAMPT (iNAMPT, the rate-limiting enzyme in the mammalian NAD main synthetic...
5.
Xu Y, Xu T, Chen S, Yao H, Chen Y, Zeng Y, et al.
PLoS One . 2023 Oct; 18(10):e0292902. PMID: 37878570
The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has swept the world and poses a serious threat to human health. In the post-pandemic-era, we...
6.
Chen S, Zheng Y, Liang B, Yin Y, Yao J, Wang Q, et al.
Eur J Med Chem . 2023 Aug; 260:115746. PMID: 37607440
Inducing protein degradation by proteolysis targeting chimera (PROTAC) has provided great opportunities for scientific research and industrial applications. Histone deacetylase (HDAC)-PROTAC has been widely developed since the first report of...
7.
Yao J, Yin Y, Han H, Chen S, Zheng Y, Liang B, et al.
Eur J Med Chem . 2022 Dec; 247:115024. PMID: 36543033
Sirtiun 5 (SIRT5) is a NAD-dependent protein lysine deacylase. It is emerging as a promising target for the development of drugs to treat cancer and metabolism-related diseases. In this study,...
8.
Chen S, Zhou B, Chen H, Yuan R
Environ Res . 2022 Nov; 216(Pt 4):114687. PMID: 36356669
In recent years, iron mediated autotrophic denitrification has been a concern because it overcomes the absence of organic carbon and has been successfully used in denitrification for low C/N ratio...
9.
Shen X, Zeng Y, Yang C, Jiang L, Chen S, Chen F, et al.
Cell Biol Int . 2022 Oct; 47(1):86-97. PMID: 36183365
Among malignant tumors, lung adenocarcinoma (LUAD) is the leading cause of death worldwide. This study explored the diagnostic, prognostic value, and preliminary functional verification of sialic acid binding Ig like...
10.
Huo M, Hu R, Zhang Q, Chen S, Gao X, Zhang Y, et al.
RSC Adv . 2022 May; 10(39):23128-23135. PMID: 35520309
In this study, PBDTTT-E (based on benzo [1,2-b:4,5-b'] dithiophene (BDT) and thieno [3,4-b] thiophene (TT)) as a donor and fullerene derivative PCBM (phenyl-C-butyric acid methyl ester) as an acceptor with...