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Shao-Lee Lin

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Articles 23
Citations 1655
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Recent Articles
11.
Gibbs J, Fredrickson J, Barbee T, Correa I, Smith B, Lin S, et al.
J Clin Pharmacol . 2011 Dec; 52(10):1494-505. PMID: 22162539
Dipeptidyl peptidase-4 (DPP-4) inhibition is a well- characterized treatment for type 2 diabetes mellitus (T2DM). The objective of this model-based meta-analysis was to describe the time course of HbA1c response...
12.
Kakkar T, Sung C, Gibiansky L, Vu T, Narayanan A, Lin S, et al.
Pharm Res . 2011 May; 28(10):2530-42. PMID: 21604075
Purpose: For AMG 317, a fully human monoclonal antibody to interleukin receptor IL-4Rα, we developed a population pharmacokinetic (PK) model by fitting data from four early phase clinical trials of...
13.
Gottlieb A, Gordon K, Giannini E, Mease P, Li J, Chon Y, et al.
J Drugs Dermatol . 2011 Mar; 10(3):289-300. PMID: 21369647
Objectives: Assessment of associations between etanercept treatment and rare adverse events has been limited by the size of clinical trial populations. The authors examined the collective safety of etanercept in...
14.
Sullivan P, Ghushchyan V, Slejko J, Belozeroff V, Globe D, Lin S
J Allergy Clin Immunol . 2011 Feb; 127(2):363-369.e1-3. PMID: 21281868
Background: It is important to have an accurate picture of the sources and extent of medical expenditures and productivity loss to understand the nature and scope of the burden of...
15.
Meltzer E, Busse W, Wenzel S, Belozeroff V, Weng H, Feng J, et al.
J Allergy Clin Immunol . 2010 Nov; 127(1):167-72. PMID: 21093024
Background: Direct correlation of assessments of a validated composite measure such as the Asthma Control Questionnaire (ACQ) and risk of exacerbation has not been previously demonstrated in a randomized controlled...
16.
Kavanaugh A, Lee S, Weng H, Chon Y, Huang X, Lin S
J Rheumatol . 2010 Feb; 37(5):1035-41. PMID: 20156946
Objective: To investigate the correlation between the Disease Activity Score using a 28-joint count (DAS28) based on physician-derived joint counts and the DAS28 based on patient-derived joint counts (Pt-DAS28) in...
17.
Corren J, Busse W, Meltzer E, Mansfield L, Bensch G, Fahrenholz J, et al.
Am J Respir Crit Care Med . 2010 Jan; 181(8):788-96. PMID: 20056900
Rationale: IL-4 and IL-13 share many biological functions important in the development of allergic airway inflammation and are implicated in the pathogenesis of asthma. AMG 317 is a fully human...
18.
Halbert R, Tinkelman D, Globe D, Lin S
J Asthma . 2009 Sep; 46(7):659-64. PMID: 19728201
Asthma control is recognized as a critical aspect of the evaluation and management of the disease. Here we evaluate and compare existing instruments for measuring asthma control in an attempt...
19.
Lovell D, Reiff A, Ilowite N, Wallace C, Chon Y, Lin S, et al.
Arthritis Rheum . 2008 Apr; 58(5):1496-504. PMID: 18438876
Objective: To evaluate the safety and efficacy of up to 8 years of etanercept treatment in patients with polyarticular-course juvenile rheumatoid arthritis (JRA). Methods: Patients with JRA who previously participated...
20.
Chamian F, Lin S, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, et al.
J Transl Med . 2007 Jun; 5:27. PMID: 17555598
Background: Alefacept (anti-CD2) biological therapy selectively targets effector memory T cells (Tem) in psoriasis vulgaris, a model Type 1 autoimmune disease. Methods: Circulating leukocytes were phenotyped in patients receiving alefacept...