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Shao-Lee Lin

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Articles 23
Citations 1655
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Recent Articles
1.
Targan S, Feagan B, Vermeire S, Panaccione R, Melmed G, Landers C, et al.
Am J Gastroenterol . 2016 Aug; 111(11):1599-1607. PMID: 27481309
Objectives: To assess the safety and efficacy of brodalumab, a human anti-interleukin-17 receptor monoclonal antibody, in patients with moderate-to-severe Crohn's disease (CD). Methods: Phase 2, randomized, double-blind, placebo-controlled, dose-ranging study...
2.
Pavelka K, Chon Y, Newmark R, Lin S, Baumgartner S, Erondu N
J Rheumatol . 2015 Apr; 42(6):912-9. PMID: 25877498
Objective: To evaluate the efficacy and safety of brodalumab, a human monoclonal antibody inhibitor of the interleukin 17 receptor, in subjects with rheumatoid arthritis (RA). Methods: Patients (n = 252)...
3.
Lin J, Zhang J, Lin S, Chertow G
Nephron . 2014 Dec; 129(1):29-33. PMID: 25531162
Background: Most patients with diabetic kidney disease (DKD) experience disease progression despite receiving standard care therapy. Oxidative stress is associated with DKD severity and risk of progression, but currently approved...
4.
DeVincenzo J, Whitley R, Mackman R, Scaglioni-Weinlich C, Harrison L, Farrell E, et al.
N Engl J Med . 2014 Aug; 371(8):711-22. PMID: 25140957
Background: Respiratory syncytial virus (RSV) is a common cause of infant hospitalizations and is increasingly recognized as a cause of considerable morbidity and mortality. No accepted antiviral treatment exists. Methods:...
5.
Sullivan P, Slejko J, Ghushchyan V, Sucher B, Globe D, Lin S, et al.
J Asthma . 2014 Apr; 51(7):769-78. PMID: 24697738
Objective: Asthma, a serious chronic lung disease affecting approximately 26 million Americans, remains clinical and economic burdens on the healthcare system. Although associations between uncontrolled asthma and poor health outcomes...
6.
Slejko J, Ghushchyan V, Sucher B, Globe D, Lin S, Globe G, et al.
J Allergy Clin Immunol . 2013 Dec; 133(6):1579-87. PMID: 24331376
Background: An estimated 23 million Americans have asthma, of whom at least 12 million experience an asthma exacerbation every year. Clinical practice guidelines focus on asthma control, with an emphasis...
7.
Busse W, Holgate S, Kerwin E, Chon Y, Feng J, Lin J, et al.
Am J Respir Crit Care Med . 2013 Nov; 188(11):1294-302. PMID: 24200404
Rationale: IL-17 signaling has been implicated in development and persistence of asthma. Cytokine-targeted strategies blocking IL-17 receptor signaling may be beneficial in asthma treatment. Objectives: To determine efficacy and safety...
8.
Sullivan P, Smith K, Ghushchyan V, Globe D, Lin S, Globe G
J Asthma . 2013 Jul; 50(8):891-9. PMID: 23815682
Objectives: Given the growing prevalence of asthma in USA, it is important to understand its national burden from the patient's perspective. The objective of this research is to examine the...
9.
Roberts N, Lewsey J, Gillies M, Briggs A, Belozeroff V, Globe D, et al.
Respir Med . 2013 May; 107(8):1172-7. PMID: 23643488
Background: The risk of case-fatality following hospitalisation for asthma has not been well characterised. We describe trends in 30 day case-fatality following hospitalisation for asthma in adults in Scotland from...
10.
Busse W, Wenzel S, Meltzer E, Kerwin E, Liu M, Zhang N, et al.
J Allergy Clin Immunol . 2012 Nov; 131(2):339-45. PMID: 23174659
Background: The D-prostanoid receptor and the chemoattractant receptor homologous molecule expressed on T(H)2 cells (CRTH2) are implicated in asthma pathogenesis. AMG 853 is a potent, selective, orally bioavailable, small-molecule dual...