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Shanliang Sun

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Articles 14
Citations 40
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Recent Articles
1.
Deng Z, Sun S, Zhou N, Peng Y, Cheng L, Yu X, et al.
Adv Sci (Weinh) . 2024 Dec; 12(5):e2407681. PMID: 39656865
Multiple myeloma (MM) is a cancer of plasma cells caused by abnormal gene expression and interactions within the bone marrow (BM) niche. The BM environment significantly influences the progression of...
2.
Cao Y, Yu T, Zhu Z, Zhang Y, Sun S, Li N, et al.
Pharmacol Ther . 2024 Nov; 265:108749. PMID: 39557344
Post-translational modifications (PTMs) play a crucial role in regulating protein function, and their dysregulation is frequently associated with various diseases. The emergence of epigenetic drugs targeting factors such as histone...
3.
Leng X, Zhang M, Xu Y, Wang J, Ding N, Yu Y, et al.
J Pharm Anal . 2024 Aug; 14(7):100947. PMID: 39149142
Cancer genomics has led to the discovery of numerous oncogenes and tumor suppressor genes that play critical roles in cancer development and progression. Oncogenes promote cell growth and proliferation, whereas...
4.
Yuan Y, Tang X, Li H, Lang X, Li C, Song Y, et al.
Front Pharmacol . 2024 Jul; 15:1400136. PMID: 38957398
Due to the similarity and diversity among kinases, small molecule kinase inhibitors (SMKIs) often display multi-target effects or selectivity, which have a strong correlation with the efficacy and safety of...
5.
Sun X, Guo C, Huang C, Lv N, Chen H, Huang H, et al.
Redox Biol . 2024 Mar; 71:103116. PMID: 38479222
Oxidative stress plays an important role in the pathogenesis of acute lung injury (ALI). As a typical post-translational modification triggered by oxidative stress, protein S-glutathionylation (PSSG) is regulated by redox...
6.
Jiang M, Yan L, Li M, Ye F, Shang E, Sun S, et al.
Comput Biol Med . 2024 Jan; 169:107868. PMID: 38211384
The San-Ao Decoction (SAD) is a well-known Traditional Chinese Medicine (TCM) formula used to alleviate respiratory symptoms, including asthma. However, its precise mechanisms of action have remained largely unknown. In...
7.
Huang H, Zhao Y, Huang C, Lv N, Zhao J, Sun S, et al.
Chem Res Toxicol . 2023 Aug; 36(9):1483-1494. PMID: 37622730
Genipin (GP) is the reactive aglycone of geniposide, the main component of traditional Chinese medicine (GF). The covalent binding of GP to cellular proteins is suspected to be responsible for...
8.
Tang C, Ke M, Yu X, Sun S, Luo X, Liu X, et al.
Adv Sci (Weinh) . 2023 Jul; 10(25):e2301264. PMID: 37439412
Tumor stemness is associated with the recurrence and incurability of colorectal cancer (CRC), which lacks effective therapeutic targets and drugs. Glycinamide ribonucleotide transformylase (GART) fulfills an important role in numerous...
9.
Gu C, Wang Y, Zhang L, Qiao L, Sun S, Shao M, et al.
J Exp Clin Cancer Res . 2023 Apr; 42(1):91. PMID: 37072818
No abstract available.
10.
Chen X, Han L, Zhao Y, Huang H, Pan H, Zhang C, et al.
Drug Metab Dispos . 2023 Mar; 51(6):771-781. PMID: 36863865
Icaritin (ICT) is a prenylflavonoid derivative that has been approved by National Medical Products Administration for the treatment of hepatocellular carcinoma. This study aims to evaluate the potential inhibitory effect...