Shankaramurthy Channabasappa
Overview
Explore the profile of Shankaramurthy Channabasappa including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
95
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Recent Articles
1.
Channabasappa S, Caldwell S, Kanthan R, Singh B
Anat Rec (Hoboken)
. 2022 Mar;
305(9):2281-2289.
PMID: 35338615
Retinoid receptors are members of nuclear receptor superfamily consisting of two distinct families: RARs (retinoic acid receptors) and RXRs (retinoid X receptors). Each family contains three receptor subtypes α, β,...
2.
Channabasappa S, Chikkamadaiah R, Durgaiah M, Kumar S, Ramesh K, Sreekanthan A, et al.
J Antimicrob Chemother
. 2018 Sep;
73(12):3398-3404.
PMID: 30215762
Objectives: P128 is a recombinant chimeric ectolysin with potent antistaphylococcal activity. P128 was evaluated as monotherapy and in combination with two standard-of-care (SoC) antibiotics, vancomycin and daptomycin, in mouse models...
3.
Nair S, Poonacha N, Desai S, Hiremath D, Tuppad D, Mohan T, et al.
J Med Microbiol
. 2018 Feb;
67(3):296-307.
PMID: 29458674
Purpose: P128, a phage-derived lysin, exerts antibacterial activity on staphylococci by cleaving the pentaglycine-bridge of peptidoglycan. We sought to determine whether the presence of P128 could re-sensitize drug-resistant bacteria to...
4.
Sharma U, Vipra A, Channabasappa S
Drug Discov Today
. 2018 Jan;
23(4):848-856.
PMID: 29326076
Bacterial biofilms are highly resistant to the action of antibiotics. Presence of persisters, phenotypically resistant populations of bacterial cells, is thought to contribute toward recalcitrance of biofilms. The phage-derived lysins,...
5.
Channabasappa S, Durgaiah M, Chikkamadaiah R, Kumar S, Joshi A, Sriram B
Antimicrob Agents Chemother
. 2017 Nov;
62(2).
PMID: 29180523
causes systemic infections with high morbidity and mortality, and the emergence of drug-resistant strains is a rapidly growing clinical concern. Novel therapeutic agents are required to tackle infections. P128 is...
6.
Schneberger D, Aulakh G, Channabasappa S, Singh B
J Occup Med Toxicol
. 2016 Jul;
11:31.
PMID: 27375768
Background: Exposure to animal barn air is an occupational hazard that causes lung dysfunction in barn workers. Respiratory symptoms experienced by workers are typically associated with endotoxin and TLR4 signalling,...
7.
Le N, Channabasappa S, Hossain M, Liu L, Singh B
Am J Physiol Lung Cell Mol Physiol
. 2015 Aug;
309(9):L995-1008.
PMID: 26320151
The mechanisms of excessive migration of activated neutrophils into inflamed lungs, credited with tissue damage, are not fully understood. We explored the hitherto unknown expression of leukocyte-specific protein 1 (LSP1)...
8.
Channabasappa S, Ferguson J, Singh B
Can J Vet Res
. 2014 Jul;
78(3):176-82.
PMID: 24982548
Retinoids play an important role in lung development and immune response. The effects of retinoids are mediated through 2 families of retinoid receptors: retinoic acid receptors (RARs) and retinoid X...
9.
Channabasappa S, Stewart S, Caldwell S, Carr A, Singh B
Vet Immunol Immunopathol
. 2013 Dec;
157(3-4):175-81.
PMID: 24359944
Activated neutrophils live longer, produce toxic metabolites and cause considerable tissue injury, which is central to the pathogenesis of many inflammatory conditions. Retinoids are a class of lipophilic compounds with...