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Shane Browne

Explore the profile of Shane Browne including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 359
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Recent Articles
1.
Petit N, Chang Y, Lobianco F, Hodgkinson T, Browne S
Mater Today Bio . 2025 Mar; 31:101596. PMID: 40083836
Hyaluronic acid (HyA) is a non-sulphated linear polysaccharide found abundantly in the extracellular matrix, known for its biocompatibility and versatility in tissue engineering. Chemical modifications of HyA, including methacrylate, acrylate,...
2.
Palomeque Chavez J, McGrath M, OConnor C, Dervan A, Dixon J, Kearney C, et al.
Biomater Sci . 2025 Feb; PMID: 40012508
Chronic wounds remain in a state of disrupted healing, impeding neurite outgrowth from injured nerves and poor development of new blood vessels by angiogenesis. Current therapeutic approaches primarily focus on...
3.
Hosty L, Heatherington T, Quondamatteo F, Browne S
Mol Biol Rep . 2024 Jul; 51(1):830. PMID: 39037470
Diabetic foot ulcers (DFU) are a debilitating and life-threatening complication of Diabetes Mellitus. Ulceration develops from a combination of associated diabetic complications, including neuropathy, circulatory dysfunction, and repetitive trauma, and...
4.
Esparza A, Jimenez N, Borrego E, Browne S, Natividad-Diaz S
Mol Biol Rep . 2024 Feb; 51(1):260. PMID: 38302762
Vascular diseases are the underlying pathology in many life-threatening illnesses. Human cellular and molecular mechanisms involved in angiogenesis are complex and difficult to study in current 2D in vitro and...
5.
Browne S, Petit N, Quondamatteo F
Cell Tissue Res . 2023 Dec; 395(2):133-145. PMID: 38051351
Diabetic foot ulcers (DFU) are a type of chronic wound that constitute one of the most serious and debilitating complications associated with diabetes. The lack of clinically efficacious treatments to...
6.
Monaghan M, Borah R, Thomsen C, Browne S
Adv Drug Deliv Rev . 2023 Oct; 203:115120. PMID: 37884128
Diabetic foot ulcers (DFUs) are a devastating complication for diabetic patients that have debilitating effects and can ultimately lead to limb amputation. Healthy wounds progress through the phases of healing...
7.
McGrath M, Zimkowska K, Genoud K, Maughan J, Gonzalez J, Browne S, et al.
ACS Appl Mater Interfaces . 2023 Mar; 15(14):17444-17458. PMID: 37001059
Chronic, nonhealing wounds in the form of diabetic foot ulcers (DFUs) are a major complication for diabetic patients. The inability of a DFU to heal appropriately leads to an open...
8.
Browne S, Gill E, Schultheiss P, Goswami I, Healy K
Stem Cell Reports . 2021 Apr; 16(9):2058-2075. PMID: 33836144
Microphysiological systems (MPSs) (i.e., tissue or organ chips) exploit microfluidics and 3D cell culture to mimic tissue and organ-level physiology. The advent of human induced pluripotent stem cell (hiPSC) technology...
9.
Dienes J, Browne S, Farjun B, Amaral Passipieri J, Mintz E, Killian G, et al.
ACS Biomater Sci Eng . 2021 Mar; 7(4):1587-1599. PMID: 33660968
Volumetric muscle loss (VML) injuries are characterized by a degree of tissue loss that exceeds the endogenous regenerative capacity of muscle, resulting in permanent structural and functional deficits. Such injuries...
10.
Browne S, Hossainy S, Healy K
ACS Biomater Sci Eng . 2021 Jan; 6(2):1135-1143. PMID: 33464856
In situ-forming hydrogels present a promising approach for minimally invasive cell transplantation and tissue regeneration. Among prospective materials, hyaluronic acid (HyA) has displayed great potential, owing to its inherent biocompatibility,...