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Shamim Naghdi

Explore the profile of Shamim Naghdi including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 429
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Recent Articles
1.
Naghdi S, Mishra P, Roy S, Weaver D, Walter L, Davies E, et al.
Nat Commun . 2025 Mar; 16(1):2416. PMID: 40069152
Differences between normal tissues and invading tumors that allow tumor targeting while saving normal tissue are much sought after. Here we show that scarcity of VDAC2, and the consequent lack...
2.
Gal A, Balicza P, Weaver D, Naghdi S, Joseph S, Varnai P, et al.
EMBO Mol Med . 2023 Jul; 15(8):e17911. PMID: 37431817
No abstract available.
3.
Naghdi S, Slovinsky W, Madesh M, Rubin E, Hajnoczky G
Cell Death Dis . 2018 Oct; 9(10):1028. PMID: 30301883
Environmental stressors like ethanol (EtOH) commonly target mitochondria to influence the cell's fate. Recent literature supports that chronic EtOH exposure suppresses mitochondrial dynamics, central to quality control, and sensitizes mitochondrial...
4.
Gal A, Balicza P, Weaver D, Naghdi S, Joseph S, Varnai P, et al.
EMBO Mol Med . 2017 May; 9(7):967-984. PMID: 28554942
The protein MSTO1 has been localized to mitochondria and linked to mitochondrial morphology, but its specific role has remained unclear. We identified a c.22G > A (p.Val8Met) mutation of MSTO1...
5.
Naghdi S, Hajnoczky G
Biochim Biophys Acta . 2016 Apr; 1863(10):2503-14. PMID: 27116927
Voltage Dependent Anion-selective Channel 2 (VDAC2) contributes to oxidative metabolism by sharing a role in solute transport across the outer mitochondrial membrane (OMM) with other isoforms of the VDAC family,...
6.
Naghdi S, Varnai P, Hajnoczky G
Proc Natl Acad Sci U S A . 2015 Sep; 112(41):E5590-9. PMID: 26417093
Voltage-dependent anion channel (VDAC) proteins are major components of the outer mitochondrial membrane. VDAC has three isoforms with >70% sequence similarity and redundant roles in metabolite and ion transport. However,...
7.
Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, et al.
Elife . 2015 Jan; 4. PMID: 25588501
Tightly regulated Ca(2+) homeostasis is a prerequisite for proper cardiac function. To dissect the regulatory network of cardiac Ca(2+) handling, we performed a chemical suppressor screen on zebrafish tremblor embryos,...
8.
Hajnoczky G, Booth D, Csordas G, Debattisti V, Golenar T, Naghdi S, et al.
Curr Opin Cell Biol . 2014 Jul; 29:133-41. PMID: 24999559
Endoplasmic reticulum (ER) and mitochondria are functionally distinct with regard to membrane protein biogenesis and oxidative energy production, respectively, but cooperate in several essential cell functions, including lipid biosynthesis, cell...
9.
Garcia-Perez C, Roy S, Naghdi S, Lin X, Davies E, Hajnoczky G
Proc Natl Acad Sci U S A . 2012 Mar; 109(12):4497-502. PMID: 22393005
Bid-induced mitochondrial membrane permeabilization and cytochrome c release are central to apoptosis. It remains a mystery how tiny amounts of Bid synchronize the function of a large number of discrete...
10.
Waldeck-Weiermair M, Duan X, Naghdi S, Jadoon Khan M, Trenker M, Malli R, et al.
Cell Calcium . 2010 Nov; 48(5):288-301. PMID: 21047682
Uncoupling proteins 2 and 3 (UCP2/3) are essential for mitochondrial Ca(2+) uptake but both proteins exhibit distinct activities in regard to the source and mode of Ca(2+) mobilization. In the...